Recent advances in clinical practice: epidemiology of autoimmune liver diseases

PJ Trivedi, GM Hirschfield - Gut, 2021 - gut.bmj.com
Autoimmune liver diseases are chronic inflammatory hepatobiliary disorders that when
classically defined encompass three distinctive clinical presentations; primary biliary …

Autoimmmune hepatitis

B Terziroli Beretta-Piccoli, G Mieli-Vergani… - Cellular & molecular …, 2022 - nature.com
Autoimmune hepatitis (AIH) is a T-cell mediated, inflammatory liver disease affecting all
ages and characterized by female preponderance, elevated serum transaminase and …

Diagnosis and management of autoimmune hepatitis

L Muratori, AW Lohse, M Lenzi - bmj, 2023 - bmj.com
Autoimmune hepatitis is an inflammatory disease of the liver of unknown cause that may
progress to liver cirrhosis and end stage liver failure if diagnosis is overlooked and treatment …

Cigarette smoking and liver diseases

D Marti-Aguado, A Clemente-Sanchez, R Bataller - Journal of hepatology, 2022 - Elsevier
Cigarette smoking is a preventable risk factor for premature morbidity and mortality. A history
of smoking is observed in approximately 40% of patients with liver disease, while a growing …

Primary biliary cholangitis: Epidemiology, prognosis, and treatment

J Trivella, BV John, C Levy - Hepatology communications, 2023 - journals.lww.com
Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease
characterized by a destructive, small duct, and lymphocytic cholangitis, and marked by the …

Global incidence and prevalence of autoimmune hepatitis, 1970–2022: a systematic review and meta-analysis

JW Hahn, HR Yang, JS Moon, JY Chang, K Lee… - …, 2023 - thelancet.com
Background Autoimmune hepatitis (AIH) varies significantly in incidence and prevalence
across countries and regions. We aimed to examine global, regional, and national trends in …

[HTML][HTML] Epidemiology, natural history, and outcomes of primary sclerosing cholangitis: a systematic review of population-based studies

PJ Trivedi, CL Bowlus, KK Yimam, H Razavi… - Clinical Gastroenterology …, 2022 - Elsevier
Background & Aims The aim of this study was to quantify the global epidemiology of primary
sclerosing cholangitis (PSC), alongside the incidence of liver transplantation, cancer, and …

Gut microbiota and chemical-induced acute liver injury

T Chen, R Li, P Chen - Frontiers in physiology, 2021 - frontiersin.org
Background: Drug overdose or chemical exposures are the main causes of acute liver injury
(ALI). Severe liver injury can develop into liver failure that is an important cause of liver …

[HTML][HTML] zVAD alleviates experimental autoimmune hepatitis in mice by increasing the sensitivity of macrophage to TNFR1-dependent necroptosis

X Li, Y Zhang, J Wang, Y Li, Y Wang, F Shi, L Hong… - Journal of …, 2022 - Elsevier
Background & aims Autoimmune hepatitis (AIH) is characterized by hepatocyte destruction,
leading to lymphocyte and macrophage accumulation in the liver. Macrophages are key …

Contemporary epidemiology of primary biliary cholangitis

F Colapietro, A Bertazzoni, A Lleo - Clinics in Liver Disease, 2022 - liver.theclinics.com
Primary biliary cholangitis (PBC) is an immune-mediated cholestatic liver disease mainly
diagnosed in middle-aged women, with a female-to-male ratio between 4 to 5: 1 and 9 to 10 …