Customized MethylC-capture sequencing to evaluate variation in the human sperm DNA methylome representative of altered folate metabolism

D Chan, X Shao, MC Dumargne… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: The sperm DNA methylation landscape is unique and critical for offspring
health. If gamete-derived DNA methylation escapes reprograming in early embryos …

[HTML][HTML] Effects of cannabis on cardiovascular system: the good, the bad, and the many unknowns

AE Dabiri, GS Kassab - Medical Cannabis and Cannabinoids, 2021 - karger.com
Cannabis is currently the most consumed illicit substance in the world, and gradual
legalization in the USA makes it important to understand the health consequences of the use …

Sperm capacitation and transcripts levels are altered by in vitro THC exposure

VB Truong, OS Davis, J Gracey, MS Neal… - BMC Molecular and Cell …, 2023 - Springer
Abstract Background Delta-9-tetrahydrocannabinol (THC) is the primary phytocannabinoid
responsible for the psychoactive properties of cannabis and is known to interact with the …

Metabolic memory of Δ9-tetrahydrocannabinol exposure in pluripotent stem cells and primordial germ cells-like cells

R Verdikt, AA Armstrong, J Cheng, YS Hwang, AT Clark… - Elife, 2023 - elifesciences.org
Cannabis, the most consumed illicit psychoactive drug in the world, is increasingly used by
pregnant women. However, while cannabinoid receptors are expressed in the early embryo …

Effects of marijuana on reproductive health: preconception and gestational effects

KS Ryan, JC Bash, CB Hanna… - Current Opinion in …, 2021 - journals.lww.com
With the increasing prevalence of marijuana use, there is an urgent need for evidence-
driven recommendations and guidelines for couples interested in conception, affected by …

Subacute cannabidiol alters genome‐wide DNA methylation in adult mouse hippocampus

NM Wanner, M Colwell, C Drown… - Environmental and …, 2020 - Wiley Online Library
Use of cannabidiol (CBD), the most abundant non‐psychoactive compound found in
cannabis (Cannabis sativa), has recently increased as a result of widespread availability of …

Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice

NM Wanner, M Colwell, C Drown, C Faulk - Clinical epigenetics, 2021 - Springer
Background Use of cannabidiol (CBD), the primary non-psychoactive compound found in
cannabis, has recently risen dramatically, while relatively little is known about the underlying …

Epidemiological associations of various substances and multiple cannabinoids with autism in USA

S Reece, G Hulse - Clinical Pediatrics: Open …, 2019 - research-repository.uwa.edu.au
Abstract Introduction: Autistic Spectrum Disorder (ASD) is increasing in across USA.
Paediatricians and physicians in both Colorado and Australia continue to see high …

Cannabis-and substance-related epidemiological patterns of chromosomal congenital anomalies in europe: geospatiotemporal and causal inferential study

AS Reece, GK Hulse - … Journal of Environmental Research and Public …, 2022 - mdpi.com
Introduction: Laboratory data link cannabinoid exposure to chromosomal mis-segregation
errors. Recent epidemiological reports confirm this link and raise concern that elevated …

Exposure to drugs of abuse induce effects that persist across generations

AM Baratta, RS Rathod, SL Plasil, A Seth… - International review of …, 2021 - Elsevier
Substance use disorders are highly prevalent and continue to be one of the leading causes
of disability in the world. Notably, not all people who use addictive drugs develop a …