[HTML][HTML] Fast Hebbian plasticity and working memory

A Lansner, F Fiebig, P Herman - Current opinion in neurobiology, 2023 - Elsevier
Theories and models of working memory (WM) were at least since the mid-1990s dominated
by the persistent activity hypothesis. The past decade has seen rising concerns about the …

A thalamic-hippocampal CA1 signal for contextual fear memory suppression, extinction, and discrimination

HC Ratigan, S Krishnan, S Smith… - Nature …, 2023 - nature.com
The adaptive regulation of fear memories is a crucial neural function that prevents
inappropriate fear expression. Fear memories can be acquired through contextual fear …

Building transformers from neurons and astrocytes

L Kozachkov, KV Kastanenka… - Proceedings of the …, 2023 - National Acad Sciences
Glial cells account for between 50% and 90% of all human brain cells, and serve a variety of
important developmental, structural, and metabolic functions. Recent experimental efforts …

Nonlinear slow-timescale mechanisms in synaptic plasticity

C O'Donnell - Current opinion in neurobiology, 2023 - Elsevier
Learning and memory rely on synapses changing their strengths in response to neural
activity. However, there is a substantial gap between the timescales of neural electrical …

A critical role for CaMKII in behavioral timescale synaptic plasticity in hippocampal CA1 pyramidal neurons

K Xiao, Y Li, RA Chitwood, JC Magee - Science Advances, 2023 - science.org
Behavioral timescale synaptic plasticity (BTSP) is a type of non-Hebbian synaptic plasticity
reported to underlie place field formation. Despite this important function, the molecular …

Structures of channelrhodopsin paralogs in peptidiscs explain their contrasting K+ and Na+ selectivities

T Morizumi, K Kim, H Li, EG Govorunova… - Nature …, 2023 - nature.com
Kalium channelrhodopsin 1 from Hyphochytrium catenoides (Hc KCR1) is a light-gated
channel used for optogenetic silencing of mammalian neurons. It selects K+ over Na+ in the …

Pixel-wise programmability enables dynamic high-SNR cameras for high-speed microscopy

J Zhang, J Newman, Z Wang, Y Qian… - Nature …, 2024 - nature.com
High-speed wide-field fluorescence microscopy has the potential to capture biological
processes with exceptional spatiotemporal resolution. However, conventional cameras …

Septo-hippocampal dynamics and the encoding of space and time

JC Robinson, JH Wilmot, ME Hasselmo - Trends in Neurosciences, 2023 - cell.com
Encoding an event in memory requires neural activity to represent multiple dimensions of
behavioral experience in space and time. Recent experiments have explored the influence …

Dendritic, delayed, and stochastic CaMKII activation underlies behavioral time scale plasticity in CA1 synapses

A Jain, Y Nakahata, T Watabe, P Rusina, KE South… - BioRxiv, 2023 - biorxiv.org
Behavioral time scale plasticity (BTSP), is a form of non-Hebbian plasticity induced by
integrating pre-and postsynaptic components separated by behavioral time scale (seconds) …

Learning, Fast and Slow: Single-and Many-Shot Learning in the Hippocampus

Z Liao, A Losonczy - Annual Review of Neuroscience, 2024 - annualreviews.org
The hippocampus is critical for memory and spatial navigation. The ability to map novel
environments, as well as more abstract conceptual relationships, is fundamental to the …