In this retrospective, we review the two research topics that formed the basis of the
outstanding career of Dr. Paul S. Frenette. In the first part, we focus on sickle cell disease …

This review provides an overview of reproductive and sexual healthcare concerns for
individuals with SCD and their families. Reproductive and sexual health care are …

Although descriptions of quality of life and patient reports of mood in sickle cell disease
(SCD) have become more common in the literature, less is known about psychiatric illness …

Sickle cell anemia (SCA) is a severe form of sickle cell disease that primarily affects black
populations and individuals in tropical countries. This condition causes significant morbidity …

Sickle cell disease (SCD) can cause both physical and psychological complications, such as
severe pain and depression. These effects often necessitate social and caregiving support …

Background Depression and other mental health disorders are prevalent among people
living with chronic health conditions. Although digital cognitive behavioral therapy (CBT) is …

Background Young adulthood brings new challenges for managing sickle cell disease.
There are fewer adult specialists, sickle cell disease morbidities accumulate, and mortality …

Despite increasing progress in the understanding of the pathophysiology of pain, current
management of pain syndromes is still unsatisfactory. The recent discovery of novel …

Objective This study examined the impact of executive functioning (EF) on adaptive
functioning and self-care independence in pre-transition youth with sickle cell disease …

Sickle cell disease (SCD) is the most common monogenic disease worldwide, with a
variable prevalence in each continent. A single nucleotide substitution leads to an amino …