Early therapeutic interventions for newly diagnosed glioblastoma: rationale and review of the literature

M Waqar, DM Trifiletti, C McBain, J O'connor… - Current oncology …, 2022 - Springer
Abstract Purpose of Review Glioblastoma is the commonest primary brain cancer in adults
whose outcomes are amongst the worst of any cancer. The current treatment pathway …

Hypofractionated radiotherapy for glioblastoma: strategy for poor-risk patients or hope for the future?

M Hingorani, WP Colley, S Dixit… - The British journal of …, 2012 - academic.oup.com
The prognosis of patients with glioblastoma (GBM) remains poor, and the use of
hyperfractionation or dose escalation beyond 60 Gy has not conferred any survival benefit …

Prognosis factors of survival time in patients with glioblastoma multiforme: a multivariate analysis of 340 patients

JF Mineo, A Bordron, M Baroncini, C Ramirez… - Acta …, 2007 - Springer
Background. The prognosis of glioblastoma multiforme remains poor despite recent
therapeutic advances. Several clinical and therapeutic factors as well as tumour …

Survival impact of time to initiation of chemoradiotherapy after resection of newly diagnosed glioblastoma

MZ Sun, T Oh, ME Ivan, AJ Clark, M Safaee… - Journal of …, 2015 - thejns.org
OBJECT There are few and conflicting reports on the effects of delayed initiation of
chemoradiotherapy on the survival of patients with glioblastoma. The standard of care for …

Delay in radiotherapy shortens survival in patients with high grade glioma

C Irwin, M Hunn, G Purdie, D Hamilton - Journal of neuro-oncology, 2007 - Springer
Fractionated external beam radiotherapy is an important component of standard treatment
for high grade glioma. Due to resource constraints, patients may experience delays in …

Resection and permanent intracranial brachytherapy using modular, biocompatible cesium-131 implants: results in 20 recurrent, previously irradiated meningiomas

DG Brachman, E Youssef, CJ Dardis, N Sanai… - Journal of …, 2018 - thejns.org
OBJECTIVE Effective treatments for recurrent, previously irradiated intracranial
meningiomas are limited, and resection alone is not usually curative. Thus, the authors …

Quantitative modeling of tumor dynamics and radiotherapy

H Enderling, MAJ Chaplain, P Hahnfeldt - Acta biotheoretica, 2010 - Springer
Cancer is a complex disease, necessitating research on many different levels; at the
subcellular level to identify genes, proteins and signaling pathways associated with the …

Impact of time to initiation of radiotherapy on survival after resection of newly diagnosed glioblastoma

S Katsigiannis, B Krischek, S Barleanu, S Grau… - Radiation …, 2019 - Springer
Background and purpose To evaluate the effect of timing of radiotherapy (RT) on survival in
patients with newly diagnosed primary glioblastoma (GBM) treated with the same …

Impact of radiotherapy delay on survival in glioblastoma

I Valduvieco, E Verger, J Bruna, L Caral, T Pujol… - Clinical and …, 2013 - Springer
Background Previous studies in glioblastoma have concluded that there is no decrease in
survival with increasing time to initiation of RT up to 6 weeks after surgery. Unfortunately, the …

[(18) F] Fluoroethyltyrosine-positron emission tomography-guided radiotherapy for high-grade glioma

DC Weber, T Zilli, F Buchegger, N Casanova… - Radiation …, 2008 - Springer
Background To compare morphological gross tumor volumes (GTVs), defined as pre-and
postoperative gadolinium enhancement on T 1-weighted magnetic resonance imaging to …