RP Joyce, VW Hu, J Wang - Medicinal Chemistry Research, 2022 - Springer
The rapid development of effective vaccines to combat the SARS-CoV-2 virus has been an effective counter measure to decrease hospitalization and the mortality rate in many …
M Sasaki, K Tabata, M Kishimoto, Y Itakura… - Science translational …, 2022 - science.org
In parallel with vaccination, oral antiviral agents are highly anticipated to act as countermeasures for the treatment of the coronavirus disease 2019 (COVID-19) pandemic …
L Rahmah, SO Abarikwu, AG Arero, M Essouma… - Pharmacological …, 2022 - Springer
The use of antiviral COVID-19 medications can successfully inhibit SARS-CoV-2 replication and prevent disease progression to a more severe form. However, the timing of antiviral …
PL Shah, CM Orton, B Grinsztejn… - The Lancet …, 2023 - thelancet.com
Background COVID-19 has overwhelmed health services globally. Oral antiviral therapies are licensed worldwide, but indications and efficacy rates vary. We aimed to evaluate the …
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2 (SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
While vaccines remain at the forefront of global healthcare responses, pioneering therapeutics against SARS-CoV-2 are expected to fill the gaps for waning immunity. Rapid …
F Tian, Z Chen, Q Feng - Journal of Medical Virology, 2023 - Wiley Online Library
At present, there are some differences in the research results of nirmatrelvir–ritonavir compared with other antiviral drugs for the treatment of COVID‐19 patients. We aimed to …
D Iacopetta, J Ceramella, A Catalano, C Saturnino… - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the Coronavirus family which caused the worldwide pandemic of human respiratory illness …
T Majerová, J Konvalinka - Molecular Aspects of Medicine, 2022 - Elsevier
Some medically important viruses―including retroviruses, flaviviruses, coronaviruses, and herpesviruses―code for a protease, which is indispensable for viral maturation and …