Hamiltonian energy as an efficient approach to identify the significant key regulators in biological networks

S Haider, K Ponnusamy, RKB Singh, A Chakraborti… - Plos one, 2019 - journals.plos.org
The topological characteristics of biological networks enable us to identify the key nodes in
terms of modularity. However, due to a large size of the biological networks with many hubs …

[PDF][PDF] Dynamics of boolean networks

F Greil - 2009 - tuprints.ulb.tu-darmstadt.de
Networks are used to model systems consisting of many interacting units. The topology of
networks has been studied extensively while there are still many open questions concerning …

Value of invertebrate genetics and biology to develop neuroprotective and preventive medicine in Huntington's disease

C Neri - Neurobiology of Huntington's disease: applications to …, 2011 - books.google.com
CONTENTS Introduction............................................................................................................ 147
Invertebrate Biology as a Path toward Preventive Medicine.................................. 149 …

Disease embryo development network reveals the relationship between disease genes and embryo development genes

B Gong, T Liu, X Zhang, X Chen, J Li, H Lv… - Journal of theoretical …, 2011 - Elsevier
A basic problem for contemporary biology and medicine is exploring the correlation between
human disease and underlying cellular mechanisms. For a long time, several efforts were …

CorSig: a general framework for estimating statistical significance of correlation and its application to gene co-expression analysis

HQ Wang, CJ Tsai - PloS one, 2013 - journals.plos.org
With the rapid increase of omics data, correlation analysis has become an indispensable
tool for inferring meaningful associations from a large number of observations. Pearson …

A top‐down systems biology approach for the identification of targets for fungal strain and process development

M Braaksma, RA van den Berg… - … Molecular Biology of …, 2010 - Wiley Online Library
This chapter discusses approaches to select targets for improvement of production
processes, with a special focus on the application of functional genomics technologies as an …

An evolving model of undirected networks based on microscopic biological interaction systems

L Tan, J Zhang, L Jiang - Journal of biological physics, 2009 - Springer
With protein or gene interaction systems as the background, this paper proposes an
evolving model of biological undirected networks, which are consistent with some plausible …

Models and algorithms for alignment of biological networks

郭杏莉, 高琳, 陈新 - Journal of Software, 2010 - jos.org.cn
生物网络比对是生物体结构, 功能和进化分析的重要研究手段. 首先给出了生物网络比对问题的
形式化定义; 其次重点分析了现有的比对模型和算法, 按照比对方法的数学特性对其进行了分类 …

A survey of human histone H1 subtypes interaction networks: Implications for histones H1 functioning

A Kowalski - Proteins: Structure, Function, and Bioinformatics, 2021 - Wiley Online Library
To show a spectrum of histone H1 subtypes (H1. 1‐H1. 5) activity realized through the
protein‐protein interactions, data selected from APID resources were processed with …

Network modules help the identification of key transport routes, signaling pathways in cellular and other networks

R Palotai, P Csermely - Annalen der Physik, 2009 - Wiley Online Library
Complex systems are successfully reduced to interacting elements via the network concept.
Transport plays a key role in the survival of networks–for example the specialized signaling …