Severe acute pancreatitis (SAP) is a critical illness characterized by a severe systemic
inflammatory response resulting in persistent multiple organ failure and sepsis. The …

Acute pancreatitis (AP) is an inflammatory disease that can progress to severe acute
pancreatitis (SAP), which increases the risk of death. AP is characterized by inappropriate …

Patients with acute pancreatitis (AP) often require ICU admission, especially when signs of
multiorgan failure are present, a condition that defines AP as severe. This disease is …

Rationale: Acute pancreatitis (AP) is a serious acute condition affecting the abdomen and
shows high morbidity and mortality rates. Its global incidence has increased in recent years …

Severe acute pancreatitis (SAP) includes persistent systemic inflammation (SIRS) and
multiorgan failure (MOF). The mechanism of transition from SIRS to MOF is unclear. We …

Diabetes represents a group of diseases involving persistent hyperglycaemia. Exocrine
disorders of the pancreas are increasingly recognised to cause or precede the onset of …

Acute pancreatitis is a disease associated with suffering and high lethality. Although the
disease mechanism is unclear, phospholipase A2 (PLA2) produced by pancreatic acinar …

Background Innate immunity and metabolites link to the pathogenesis and severity of acute
pancreatitis (AP). However, liver metabolism and its role in immune response and AP …

The gut microbiome is a complex microbial community, recognized for its potential role in
physiology, health, and disease. The available evidence supports the role of gut dysbiosis in …

Severe acute pancreatitis-associated acute lung injury (SAP-ALI) is a serious disease
associated with high mortality. Emodin has been applied to alleviate SAP-ALI; however, the …