[HTML][HTML] Chaiqin chengqi decoction alleviates severity of acute pancreatitis via inhibition of TLR4 and NLRP3 inflammasome: identification of bioactive ingredients via …

Y Wen, C Han, T Liu, R Wang, W Cai, J Yang, G Liang… - Phytomedicine, 2020 - Elsevier
Background Chaiqin chengqi decoction (CQCQD) is a Chinese herbal formula derived from
dachengqi decoction. CQCQD has been used for the management of acute pancreatitis (AP) …

Matrine alleviates oxidative stress and ferroptosis in severe acute pancreatitis-induced acute lung injury by activating the UCP2/SIRT3/PGC1α pathway

H Jin, K Zhao, J Li, Z Xu, S Liao, S Sun - International …, 2023 - Elsevier
Acute lung injury (ALI) is one of the most serious complications of severe acute pancreatitis
(SAP). Matrine is well known for its powerful antioxidant and antiapoptotic properties …

Comprehensive review on the pathogenesis of hypertriglyceridaemia-associated acute pancreatitis

M Qiu, X Zhou, M Zippi, H Goyal, Z Basharat… - Annals of …, 2023 - Taylor & Francis
It is well known, that the inflammatory process that characterizes acute pancreatitis (AP) can
lead to both pancreatic damage and systemic inflammatory response syndrome (SIRS) …

Gut dysbiosis in pancreatic diseases: A causative factor and a novel therapeutic target

T Zhang, G Gao, HA Sakandar, LY Kwok, Z Sun - Frontiers in Nutrition, 2022 - frontiersin.org
Pancreatic-related disorders such as pancreatitis, pancreatic cancer, and type 1 diabetes
mellitus (T1DM) impose a substantial challenge to human health and wellbeing. Even …

Postoperative serum hyperamylasemia adds sequential value to the fistula risk score in predicting pancreatic fistula after pancreatoduodenectomy

E Bannone, G Marchegiani, C Vollmer, G Perri… - Annals of …, 2023 - journals.lww.com
Objective: To evaluate whether postoperative serum hyperamylasemia (POH), with drain
fluid amylase (DFA) and C-reactive protein (CRP), improves the Fistula Risk Score (FRS) …

[HTML][HTML] A microRNA checkpoint for Ca2+ signaling and overload in acute pancreatitis

W Du, G Liu, N Shi, D Tang, PE Ferdek… - Molecular Therapy, 2022 - cell.com
Acute pancreatitis (AP) is a common digestive disease without specific treatment, and its
pathogenesis features multiple deleterious amplification loops dependent on translation …

Management of severe acute pancreatitis

PJ Lee, GI Papachristou - Current treatment options in gastroenterology, 2020 - Springer
Purpose of review There have been significant advancements in different aspects of
management of severe acute pancreatitis (SAP). Our review of the most recent literature …

Composition and functional profiles of gut microbiota reflect the treatment stage, severity, and etiology of acute pancreatitis

Z Wang, M Guo, J Li, C Jiang, S Yang… - Microbiology …, 2023 - Am Soc Microbiol
Acute pancreatitis (AP) is a type of digestive system disease with high mortality. Previous
studies have shown that gut microbiota can participate in developing and treating acute …

Inhibition of the PERK/TXNIP/NLRP3 axis by Baicalin reduces NLRP3 inflammasome‐mediated pyroptosis in macrophages infected with Mycobacterium tuberculosis

Y Fu, J Shen, Y Li, F Liu, B Ning… - Mediators of …, 2021 - Wiley Online Library
Mycobacterium tuberculosis (Mtb) remains a significant threat to global health as it induces
granuloma and systemic inflammatory responses during active tuberculosis. Mtb can induce …

[HTML][HTML] Alteration of gut microbiota in acute pancreatitis and associated therapeutic strategies

Y Zhu, Q Mei, Y Fu, Y Zeng - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Gut microbiome is considered as a crucial regulator of human health. Alteration of gut
microbiome has been reported in acute pancreatitis (AP) and probably contributes to the …