Identification of AP-1 as a critical regulator of glutathione peroxidase 4 (GPX4) transcriptional suppression and acinar cell ferroptosis in acute pancreatitis

X Ma, X Dong, Y Xu, N Ma, M Wei, X Xie, Y Lu, W Cao… - Antioxidants, 2022 - mdpi.com
Glutathione peroxidase 4 (GPX4)-dependent ferroptosis in pancreatic acinar cells plays a
critical role in acute pancreatitis (AP). However, potential upstream regulators of GPX4 are …

Damage associated molecular patterns and neutrophil extracellular traps in acute pancreatitis

X Zhou, S Jin, J Pan, Q Lin, S Yang… - Frontiers in Cellular …, 2022 - frontiersin.org
Previous researches have emphasized a trypsin-centered theory of acute pancreatitis (AP)
for more than a century. With additional studies into the pathogenesis of AP, new …

Bibliometric analysis of acute pancreatitis in Web of Science database based on CiteSpace software

W Sun, P Huang, H Song, D Feng - Medicine, 2020 - journals.lww.com
Objectives: Recent years have witnessed some controversial viewpoints in clinical and basic
research, which exert a great influence on the research trend of acute pancreatitis (AP). We …

Precision medicine in pancreatitis: the future of acute pancreatitis care

A Garami, P Hegyi - Function, 2023 - academic.oup.com
Acute pancreatitis (AP) continues to present a substantial burden to patients and healthcare
personnel. Despite its occasionally severe progression and high mortality rate, there is no …

Stress hyperglycemia is independently associated with persistent organ failure in acute pancreatitis

X Yang, R Zhang, T Jin, P Zhu, L Yao, L Li… - Digestive diseases and …, 2022 - Springer
Abstract Background/Aims Stress hyperglycemia is common in critical illness but it has not
been clearly studied in patients with acute pancreatitis (AP). This study aimed to investigate …

[HTML][HTML] Material basis and molecular mechanisms of Dachengqi decoction in the treatment of acute pancreatitis based on network pharmacology

W Sun, Y Chen, H Li, H Liu, J Li, J Chen… - Biomedicine & …, 2020 - Elsevier
Background Dachengqi decoction (DCQD) is a classical prescription in traditional Chinese
medicine (TCM). It has been used to treat abdominal pain and acute pancreatitis (AP) for …

Identification of novel immune-related targets mediating disease progression in acute pancreatitis

Q Liu, L Li, D Xu, J Zhu, Z Huang, J Yang… - Frontiers in Cellular …, 2022 - frontiersin.org
Introduction Acute pancreatitis (AP) is an inflammatory disease with very poor outcomes.
However, the order of induction and coordinated interactions of systemic inflammatory …

In situ neutrophil apoptosis and macrophage efferocytosis mediated by Glycyrrhiza protein nanoparticles for acute inflammation therapy

X Liu, X Ou, T Zhang, X Li, Q Qiao, L Jia, Z Xu… - Journal of Controlled …, 2024 - Elsevier
In the progression of acute inflammation, the activation and recruitment of macrophages and
neutrophils are mutually reinforcing, leading to amplified inflammatory response and severe …

A multi-strategy platform for quality control and Q-markers screen of Chaiqin chengqi decoction

G Liang, J Yang, T Liu, S Wang, Y Wen, C Han… - Phytomedicine, 2021 - Elsevier
Background Acute pancreatitis (AP) is an inflammatory disorder of the pancreas that is
associated with substantial morbidity and mortality. Chaiqin chengqi decoction (CQCQD) …

Recent Treatment Strategies for Acute Pancreatitis

Y Song, SH Lee - Journal of clinical medicine, 2024 - mdpi.com
Acute pancreatitis (AP) is a leading gastrointestinal disease that causes hospitalization.
Initial management in the first 72 h after the diagnosis of AP is pivotal, which can influence …