[HTML][HTML] Neddylation-mediated degradation of hnRNPA2B1 contributes to hypertriglyceridemia pancreatitis

W Chen, Y Wang, W Xia, J Zhang, Y Zhao - Cell Death & Disease, 2022 - nature.com
Hypertriglyceridemia-induced acute pancreatitis (HTGP) is characterized by the acute and
excessive release of FFA produced by pancreatic lipases. However, the underlying …

[HTML][HTML] Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis

N Ma, C Yuan, J Shi, Q Zhu, Y Liu, X Ma, B Li, W Gong… - JCI insight, 2022 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a local and/or systemic inflammatory disease that starts with acinar
cell injury and necrosis; it has no effective medical treatment and thus remains a life …

[HTML][HTML] Long noncoding RNA H19 regulates the therapeutic efficacy of mesenchymal stem cells in rats with severe acute pancreatitis by sponging miR-138-5p and …

G Song, J Zhou, R Song, D Liu, W Yu, W Xie… - Stem cell research & …, 2020 - Springer
Background Patients with severe acute pancreatitis (SAP), which is characterized by high
morbidity and mortality, account for an increasing medical burden worldwide. We previously …

[HTML][HTML] Real-time prediction of organ failures in patients with acute pancreatitis using longitudinal irregular data

J Luo, L Lan, S Huang, X Zeng, Q Xiang, M Li… - Journal of Biomedical …, 2023 - Elsevier
It is extremely important to identify patients with acute pancreatitis who are at high risk for
developing persistent organ failures early in the course of the disease. Due to the irregularity …

Colonic mucin‐2 attenuates acute necrotizing pancreatitis in rats by modulating intestinal homeostasis

Z Huang, H Wu, J Fan, Q Mei, Y Fu, N Yin… - The FASEB …, 2023 - Wiley Online Library
Abstract Mucin‐2 (MUC2) secreted by goblet cells participates in the intestinal barrier, but its
mechanism in acute necrotizing pancreatitis (ANP) remains unclear. In acute pancreatitis …

Disulfiram reduces the severity of mouse acute pancreatitis by inhibiting RIPK1-dependent acinar cell necrosis

QY Huang, R Zhang, QY Zhang, C Dai, XY Yu… - Bioorganic …, 2023 - Elsevier
Acute pancreatitis (AP) is a frequent abdominal inflammatory disease. Despite the high
morbidity and mortality, the management of AP remains unsatisfactory. Disulfiram (DSF) is …

Novel Amphibian Bowman–Birk-Like Inhibitor with Antioxidant and Anticoagulant Effects Ameliorates Pancreatitis Symptoms in Mice

J Chai, J Wu, J Li, H Liao, W Lu, R Guo… - Journal of Medicinal …, 2023 - ACS Publications
Acute pancreatitis (AP) is a serious inflammatory disorder and still lacks effective therapy
globally. In this study, a novel Ranacyclin peptide, Ranacin, was identified from the skin of …

[HTML][HTML] Mogroside IIE Inhibits Digestive Enzymes via Suppression of Interleukin 9/Interleukin 9 Receptor Signalling in Acute Pancreatitis

J Xiao, K Huang, H Lin, Z Xia, J Zhang, D Li… - Frontiers in …, 2020 - frontiersin.org
The incidence of pancreatitis (AP) is increasing and there is no specific treatment available.
Intracellular digestive enzyme activation is a key event in the pathogenesis of AP …

Preexisting diabetes, serum calcium and D-dimer levels as predictable risk factors for pancreatic necrosis of patients with acute pancreatitis: a retrospective study

E Xue, Q Shi, S Guo, X Zhang, C Liu… - Expert Review of …, 2022 - Taylor & Francis
Background Some individuals with acute pancreatitis (AP) suffer from pancreatic necrosis.
Diabetes affects the severity of AP, but whether diabetes influences pancreatic necrosis is …

[HTML][HTML] Cytokines and inflammatory mediators: Markers involved in interstitial damage to the pancreas in two dengue fever cases associated with acute pancreatitis

FAV Alves, LLS Oliveira, NG Salomão… - PLoS …, 2022 - journals.plos.org
Dengue viral (DENV) infections can lead to acute pancreatitis and associated tissue
damage. This study examined the pancreas from two fatal cases of DENV for …