The role and therapeutic potential of NF-kappa-B pathway in severe COVID-19 patients
A Hariharan, AR Hakeem, S Radhakrishnan… - …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) pandemic has affected health care systems
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …
The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19
Abstract The coronavirus disease (COVID-19) has once again reminded us of the
significance of host immune response and consequential havocs of the immune …
significance of host immune response and consequential havocs of the immune …
Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention
E Shirbhate, J Pandey, VK Patel, M Kamal… - Pharmacological …, 2021 - Springer
Angiotensin-converting enzyme (ACE) and its homologue, ACE2, are commonly allied with
hypertension, renin–angiotensin–aldosterone system pathway, and other cardiovascular …
hypertension, renin–angiotensin–aldosterone system pathway, and other cardiovascular …
Virus-mediated cell-cell fusion
Cell-cell fusion between eukaryotic cells is a general process involved in many
physiological and pathological conditions, including infections by bacteria, parasites, and …
physiological and pathological conditions, including infections by bacteria, parasites, and …
Corticosteroids for COVID-19 therapy: potential implications on tuberculosis
R Gopalaswamy, S Subbian - International journal of molecular sciences, 2021 - mdpi.com
On 11 March 2020, the World Health Organization announced the Corona Virus Disease-
2019 (COVID-19) as a global pandemic, which originated in China. At the host level, COVID …
2019 (COVID-19) as a global pandemic, which originated in China. At the host level, COVID …
Cannabinoids alleviate the LPS-induced cytokine storm via attenuating NLRP3 inflammasome signaling and TYK2-mediated STAT3 signaling pathways in vitro
SV Suryavanshi, M Zaiachuk, N Pryimak, I Kovalchuk… - Cells, 2022 - mdpi.com
Cannabinoids, mainly cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), are the most
studied group of compounds obtained from Cannabis sativa because of their several …
studied group of compounds obtained from Cannabis sativa because of their several …
SARS-CoV-2 switches 'on'MAPK and NFκB signaling via the reduction of nuclear DUSP1 and DUSP5 expression
S Goel, F Saheb Sharif-Askari… - Frontiers in …, 2021 - frontiersin.org
Mitogen-activated protein kinases (MAPK) and NF-kappaB (NF-κB) pathway regulate many
cellular processes and are essential for immune cells function. Their activity is controlled by …
cellular processes and are essential for immune cells function. Their activity is controlled by …
p53/NF-kB balance in SARS-CoV-2 infection: From OMICs, genomics and pharmacogenomics insights to tailored therapeutic perspectives (COVIDomics)
D Milani, L Caruso, E Zauli, AM Al Owaifeer… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infection affects different organs and tissues, including the upper and lower
airways, the lung, the gut, the olfactory system and the eye, which may represent one of the …
airways, the lung, the gut, the olfactory system and the eye, which may represent one of the …
Traditional uses, pharmacological effects, and molecular mechanisms of licorice in potential therapy of COVID-19
Q Zhang, H Huang, M Qiu, Z Wu, Z Xin, X Cai… - Frontiers in …, 2021 - frontiersin.org
The current Coronavirus disease 2019 (COVID-19) pandemic has become a global
challenge, and although vaccines have been developed, it is expected that mild to moderate …
challenge, and although vaccines have been developed, it is expected that mild to moderate …
Mechanisms leading to gut dysbiosis in COVID-19: current evidence and uncertainties based on adverse outcome pathways
LA Clerbaux, J Filipovska, A Muñoz, M Petrillo… - Journal of Clinical …, 2022 - mdpi.com
Alteration in gut microbiota has been associated with COVID-19. However, the underlying
mechanisms remain poorly understood. Here, we outlined three potential interconnected …
mechanisms remain poorly understood. Here, we outlined three potential interconnected …