This review focuses on current tissue engineering strategies for promoting vascularized
bone regeneration. We review the role of angiogenic growth factors in promoting …

Bone Tissue engineering (BTE) has recently been introduced as an alternative to
conventional treatments for large non-healing bone defects. BTE approaches mimic …

Musculoskeletal disease and injury are highly prevalent conditions that lead to many
surgical procedures. Autologous tissue transfer, allograft transplantation and nontissue …

In the past three decades, tissue engineering has made great progress in fabricating various
artificial tissues with simple structures, achieving partially functional restoration in …

Bone is a highly vascularized tissue, in which vascularization and mineralization are
concurrent processes during skeletal development. Indeed, both components should be …

Natural bone is a highly vascularized tissue that relies on blood vessels for the timely supply
of blood and nutrition to maintain skeletal integrity.[1, 2] Thus in bone regeneration the newly …

Complex three-dimensional (3D) pore geometries, useful for tissue engineering scaffolds,
can be fabricated via photo-crosslinking of resorbable poly (propylene fumarate)(PPF) …

The need for bone grafts is tremendous, and that leads to the use of autograft, allograft, and
bone graft substitutes. The biology of the bone is quite complex regarding cellular …

Developing a highly bioactive bone tissue engineering scaffold that can modulate the bone
remodeling process for promoting bone regeneration is a great challenge. In order to tackle …

Although bone has great capacity for repair, there are a number of clinical situations
(fracture non‐unions, spinal fusions, revision arthroplasty, segmental defects) in which auto …