As recognized by several international agencies, antibiotic resistance is nowadays one of
the most relevant problems for human health. While this problem was alleviated with the …

Sepsis remains a critical global health issue, demanding novel therapeutic strategies.
Traditional immunomodulation treatments such as corticosteroids, specific modifiers of …

Acute kidney injury (AKI) is a common complication of sepsis. Eupatilin (EUP) is a natural
flavone with multiple biological activities and has beneficial effects against various …

Background Sepsis is recognized as a multiorgan and systemic damage caused by
dysregulated host response to infection. Its acute systemic inflammatory response highly …

Background Sepsis is a life-threatening disorder with no definitive cure. Preclinical studies
suggest that extracellular vesicles derived from mesenchymal stromal cells (EV-MSCs) can …

Sepsis is a multi-organ dysfunction characterized by an unregulated host response to
infection. It is associated with high morbidity, rapid disease progression, and high mortality …

Multidrug-resistant sepsis (MDR) is a pressing concern in intensive care unit (ICU) settings,
specifically among geriatric patients who experience age-related immune system changes …

脓毒症是由创伤, 感染等引起的临床急危重综合征, 其患病率和死亡率在全球范围内居高不下.
随着对脓毒症病理生理机制研究的深入, 免疫调节逐渐成为该领域研究热点, 而T …

Hypercytokinemia, the renin-angiotensin system, hypoxia, immune dysregulation, and
vasculopathy with evidence of immune-related damage are implicated in brain morbidity in …

This research utilized single‐cell RNA sequencing to map the immune cell landscape in
sepsis, revealing 28 distinct cell clusters and categorizing them into nine major types …