Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …

Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Background: The ability to isolate extracellular vesicles (EVs) from blood is vital in the
development of EVs as disease biomarkers. Both serum and plasma can be used, but few …

Integrins are a family of transmembrane glycoprotein signaling receptors that can transmit
bioinformation bidirectionally across the plasma membrane. Integrin αIIbβ3 is expressed at a …

Platelets are the smallest blood cells, numbering 150 to 350× 10 9/L in healthy individuals.
The ability of activated platelets to adhere to an injured vessel wall and form aggregates was …

Wound healing is an important function of skin; however, after significant skin injury (burns)
or in certain dermatological pathologies (chronic wounds), this important process can be …

Integrin αIIbβ3 is a highly abundant heterodimeric platelet receptor that can transmit
information bidirectionally across the plasma membrane, and plays a critical role in …

Platelets are essential for clotting in the blood and maintenance of normal hemostasis.
Under pathologic conditions such as atherosclerosis, vascular injury often results in …

Knowledge of the identity and quantity of expressed proteins of a cell type is a prerequisite
for a complete understanding of its molecular functions. Mass-spectrometry-based …

Fluid resuscitation after massive hemorrhage in major surgery and trauma may result in
extensive hemodilution and coagulopathy, which is of a multifactorial nature. Although …