Functional cure of chronic hepatitis B (CHB)—or hepatitis B surface antigen (HBsAg) loss
after 24 weeks off therapy—is now the goal of treatment, but is rarely achieved with current …

The immune system employs recognition tools to communicate with its microbial
evolutionary partner. Among all the methods of microbial perception, T cells enable the …

The extent to which immune responses to natural infection with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and immunization with vaccines protect against …

Mucosal-associated invariant T (MAIT) cells represent an abundant innate-like T cell
subtype in the human liver. MAIT cells are assigned crucial roles in regulating immunity and …

Replication-incompetent adenovirus (Ad) vectors have been widely used as gene delivery
vehicles in both gene therapy studies and basic studies for gene function analysis due to …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Abstract Mucosal Associated Invariant T (MAIT) cells are evolutionary conserved innate-like
T cells able to recognize bacterial and fungal ligands derived from vitamin B biosynthesis …

Members of the coronaviridae family are endemic to human populations and have caused
several epidemics and pandemics in recent history. In this review, we will discuss the …

Human mucosal-associated invariant T (MAIT) cells are characterized by their expression of
an invariant TCR α chain Vα7. 2-Jα33/Jα20/Jα12 paired with a restricted TCR β chain. MAIT …

Prior studies have demonstrated that immunologic dysfunction underpins severe illness in
COVID-19 patients, but have lacked an in-depth analysis of the immunologic drivers of death …