This study investigated the possible anti-inflammatory and chondroprotective effects of a
combination of celecoxib and prescription-grade glucosamine sulfate (GS) in human …

Objectives Osteoarthritis (OA) features ageing-related defects in cellular homeostasis
mechanisms in articular cartilage. These defects are associated with suppression of …

Background Osteoarthritis is a common cause of pain and disability with an increasing
prevalence among the global population (Hunter and Bierma-Zeinstra in Lancet 393 …

Many factors may trigger intervertebral disc (IVD) structural failure (intervertebral disc
degeneration (IDD) and endplate changes), including inflammation, infection, dysbiosis, and …

The relation between obesity and osteoarthritis (OA) development has been traditionally
explained as consequence of the excessive joint effort derived of overweight. However, in …

Bone aging is characterized by an imbalance in the physiological and pathological
processes of osteogenesis, osteoclastogenesis, adipogenesis, and chondrogenesis …

Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage
damage and synovial inflammation and carries an enormous public health and economic …

Objective Osteoporosis (OP), clinically featured with a low bone mineral density (BMD) and
high risk of bone fracture, has become a major risk factor of disability and death in the …

Osteoarthritis (OA) is a common degenerative joint disease that can cause severe pain,
motor dysfunction, and even disability. A growing body of research indicates that gut …

Chondroitin sulfate (CS) has widely been used as a symptomatic slow-acting drug or a
dietary supplement for the treatment and prevention of osteoarthritis. However, CS could not …