Trends in HIV-1 pretreatment drug resistance and HIV-1 variant dynamics among antiretroviral therapy-naive Ethiopians from 2003 to 2018: a pooled sequence …
Background Ethiopia is among the highly HIV-affected countries, with reported 12,000 and
12,000 AIDS-related deaths and incidents as per reports from 2021. Although the country …
12,000 AIDS-related deaths and incidents as per reports from 2021. Although the country …
Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study
A Nel, N Van Niekerk, B Van Baelen, M Malherbe… - The Lancet …, 2021 - thelancet.com
Summary Background The Ring Study, a phase 3 trial in 1959 sexually active women
(randomised 2: 1), showed a favourable safety profile and a 31% HIV-1 infection risk …
(randomised 2: 1), showed a favourable safety profile and a 31% HIV-1 infection risk …
Trends in pretreatment HIV-1 drug resistance in antiretroviral therapy-naive adults in South Africa, 2000–2016: a pooled sequence analysis
B Chimukangara, RJ Lessells, SY Rhee… - …, 2019 - thelancet.com
Abstract Background South Africa has the largest public antiretroviral therapy (ART)
programme in the world. We assessed temporal trends in pretreatment HIV-1 drug …
programme in the world. We assessed temporal trends in pretreatment HIV-1 drug …
Assessment of HIV transfusion transmission risk in South Africa: a 10‐year analysis following implementation of individual donation nucleic acid amplification …
M Vermeulen, N Lelie, C Coleman, W Sykes… - …, 2019 - Wiley Online Library
BACKGROUND In 1998 we estimated that 34/million infectious window period donations
were entering the blood supply at the South African National Blood Service. Selective use of …
were entering the blood supply at the South African National Blood Service. Selective use of …
Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: a narrative overview
PO Bessong, ND Matume, DM Tebit - AIDS Research and Therapy, 2021 - Springer
Abstract Background South Africa, with one of the highest HIV prevalences in the world,
introduced the universal test and treat (UTT) programme in September 2016. Barriers to …
introduced the universal test and treat (UTT) programme in September 2016. Barriers to …
HIV drug resistance profile in South Africa: findings and implications from the 2017 national HIV household survey
Background HIV drug resistance (HIVDR) testing was included in the 2017 South African
national HIV household survey. We describe the prevalence of HIVDR by drug class, age …
national HIV household survey. We describe the prevalence of HIVDR by drug class, age …
Impact of next-generation sequencing defined human immunodeficiency virus pretreatment drug resistance on virological outcomes in the ANRS 12249 treatment-as …
A Derache, CC Iwuji, K Baisley… - Clinical Infectious …, 2019 - academic.oup.com
Background Previous studies in human immunodeficiency virus (HIV)-positive individuals on
thymidine analogue backbone antiretroviral therapy (ART) with either nevirapine or …
thymidine analogue backbone antiretroviral therapy (ART) with either nevirapine or …
Human immunodeficiency virus (HIV) drug resistance in African infants and young children newly diagnosed with HIV: a multicountry analysis
MR Jordan, M Penazzato, A Cournil… - Clinical Infectious …, 2017 - academic.oup.com
Background Programs for the prevention of mother-to-child transmission (PMTCT) of human
immunodeficiency virus (HIV) have been scaled up in many low-and middle-income …
immunodeficiency virus (HIV) have been scaled up in many low-and middle-income …
Drug resistance, rather than low tenofovir levels in blood or urine, is associated with tenofovir, emtricitabine, and efavirenz failure in resource-limited settings
The high cost of viral load (VL) testing limits its use for antiretroviral therapy (ART)
adherence support. A low-cost lateral flow urine tenofovir (TFV) rapid assay predicts pre …
adherence support. A low-cost lateral flow urine tenofovir (TFV) rapid assay predicts pre …
Low prevalence of pre-treatment and acquired drug resistance to Dolutegravir among treatment naive individuals initiating on Tenofovir, lamivudine and Dolutegravir …
V Kouamou, T Washaya, CE Ndhlovu, J Manasa - Viruses, 2023 - mdpi.com
Dolutegravir (DTG) use in combination with tenofovir and lamivudine (TLD) is scaling up in
Africa. However, HIV drug resistance (HIVDR) data to DTG remain scarce in Zimbabwe. We …
Africa. However, HIV drug resistance (HIVDR) data to DTG remain scarce in Zimbabwe. We …