Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with a significant
unmet medical need. Development of transformational therapies for IPF is challenging in …

'Oxidative stress'(OS) refers to the deviations in redox biology inside biological systems. This
term has been used to illustrate the imbalance between oxidants and antioxidants, which …

This study explored the profibrotic impact of high glucose in the lung and potential
mechanisms using latent TGF-β1-induced human epithelial cell pulmonary fibrosis and …

In the longtime challenge of identifying specific, easily detectable and reliable biomarkers of
IPF, BALF proteomics is providing interesting new insights into its pathogenesis. To the best …

Idiopathic pulmonary fibrosis is a lethal lung fibroproliferative disease with limited
therapeutic options. Differential expression profiling of affected sites has been instrumental …

Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by severe lung
fibrosis and a poor prognosis. Although the biomolecules related to IPF have been …

Objective. Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, high‐
mortality lung disease, but its pathogenesis is still unclear. Our purpose was to explore …

Honeycombing is a histological pattern consistent with Usual Interstitial Pneumonia (UIP).
Honeycombing refers to cystic airways located at sites of dense fibrosis with marked mucus …

The unknown aetiology of irreversible fibrotic scarring of lung tissues in Idiopathic
Pulmonary Fibrosis (IPF) has resulted in the lack of a gold standard for disease diagnosis …

Numerous published papers are investigating the utility of biomarkers in Idiopathic
Pulmonary Fibrosis (IPF) diagnosis, treatment, and outcome prediction. This chapter will …