[HTML][HTML] Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway

H Huang, T Wang, L Wang, Y Huang, W Li, Y Hu… - Experimental …, 2023 - Elsevier
Heart disease is a significant health concern for elderly individuals, with heart aging being
the primary cause. Recent studies have shown that autophagy can play a protective role in …

Sepsis‐associated encephalopathy: Autophagy and miRNAs regulate microglial activation

N Qin, Y Miao, L Xie, X Ma, P Xie - Physiological Reports, 2024 - Wiley Online Library
Sepsis‐associated encephalopathy (SAE) describes diffuse or multifocal cerebral
dysfunction caused by the systemic inflammatory response to sepsis. SAE is a common …

[HTML][HTML] Total saponins from Panax japonicus promote lipolysis of aging fat through the tyrosine hydroxylase signaling pathway

M Xue, W Wu, G Zhou, J Zhang, S Wang, Y Hu… - Journal of Functional …, 2024 - Elsevier
Aging and obesity are closely related. A key change in the adipose tissue during the aging
process is the decline of lipolysis. The excitation of the sympathetic nerve system is a key …

Phytochemistry and Pharmacological Activities of Panax japonicus: A Comprehensive Review

L Wang, A Zhou, Y Zhang, C Fan, S Hu… - Pharmacognosy …, 2024 - journals.sagepub.com
Background Panax japonicus (P. japonicus) belongs to the Panax genus of Araliaceae and
is used as medicine mainly with the bamboo whiplike rhizome, which has the functions of …

Structural characterization of Hericium coralloides polysaccharide and its neuroprotective function in Alzheimer's disease

Y Guan, C Wang, L Li, X Dai, Y Liu, T Hsiang… - International Journal of …, 2024 - Elsevier
Alzheimer's disease (AD) is a common neurodegenerative disorder. Polysaccharides have
been scientifically demonstrated to possess neuroprotective properties. In this study, a …

[HTML][HTML] The antiangiogenic effect of total saponins of Panax japonicus CA Meyer in rheumatoid arthritis is mediated by targeting the HIF-1α/VEGF/ANG-1 axis

X Guo, J Zhang, Z Feng, J Ji, X Shen, X Hou… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese herbal medicine Panax
japonicus CA Meyer has a long history in clinical treatment of rheumatoid arthritis (RA). Total …