Structural biology of SARS-CoV-2: open the door for novel therapies
W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
COVID-19 and the role of cytokines in this disease
A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
COVID-19 and rheumatoid arthritis crosstalk: emerging association, therapeutic options and challenges
Hyperactivation of immune responses resulting in excessive release of pro-inflammatory
mediators in alveoli/lung structures is the principal pathological feature of coronavirus …
mediators in alveoli/lung structures is the principal pathological feature of coronavirus …
Multisystem inflammatory syndrome and autoimmune diseases following COVID-19: molecular mechanisms and therapeutic opportunities
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), has led to huge concern worldwide. Some SARS-CoV-2 …
coronavirus 2 (SARS-CoV-2), has led to huge concern worldwide. Some SARS-CoV-2 …
Drugs for COVID-19: An update
J Ceramella, D Iacopetta, MS Sinicropi, I Andreu… - Molecules, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the seventh
known human coronavirus, and it was identified in Wuhan, Hubei province, China, in 2020. It …
known human coronavirus, and it was identified in Wuhan, Hubei province, China, in 2020. It …
Cefiderocol treatment for carbapenem-resistant Acinetobacter baumannii infection in the ICU during the COVID-19 pandemic: a multicentre cohort study
R Pascale, Z Pasquini, M Bartoletti… - JAC-antimicrobial …, 2021 - academic.oup.com
Objectives To analyse the impact of cefiderocol use on outcome in patients admitted to the
ICU for severe COVID-19 and further diagnosed with carbapenem-resistant Acinetobacter …
ICU for severe COVID-19 and further diagnosed with carbapenem-resistant Acinetobacter …
From Infection to Immunity: Understanding the Response to SARS-CoV2 Through In-Silico Modeling
Background Immune system conditions of the patient is a key factor in COVID-19 infection
survival. A growing number of studies have focused on immunological determinants to …
survival. A growing number of studies have focused on immunological determinants to …
Targeting the PI3K/Akt/mTOR pathway: A therapeutic strategy in COVID-19 patients
Some COVID-19 patients suffer complications from anti-viral immune responses which can
lead to both a dangerous cytokine storm and development of blood-borne factors that render …
lead to both a dangerous cytokine storm and development of blood-borne factors that render …
Newly emerged antiviral strategies for SARS-CoV-2: From deciphering viral protein structural function to the development of vaccines, antibodies, and small molecules
Coronavirus disease 2019 (COVID-19) caused by the infection of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has become the most severe health crisis, causing …
syndrome coronavirus 2 (SARS-CoV-2) has become the most severe health crisis, causing …
Cellular metabolic basis of altered immunity in the lungs of patients with COVID-19
S Li, F Zhao, J Ye, K Li, Q Wang, Z Du, Q Yue… - Medical microbiology …, 2022 - Springer
Metabolic pathways drive cellular behavior. Severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection causes lung tissue damage directly by targeting cells or indirectly …
2 (SARS-CoV-2) infection causes lung tissue damage directly by targeting cells or indirectly …