Carcinogenesis cannot be explained only by genetic alterations, but also involves
epigenetic processes. Modification of histones by acetylation plays a key role in epigenetic …

Simple Summary Beyond mutations, epigenetic changes have been described as drivers for
cancer as well. While leaving the overall DNA structure intact, they can be responsible for …

Histone deacetylase (HDAC) inhibitors are powerful epigenetic regulators that have
enormous therapeutic potential and have pleiotropic effects at the cellular and systemic …

The alteration of age‐related molecules in the bone marrow microenvironment is one of the
driving forces in osteoporosis. These molecules inhibit bone formation and promote bone …

The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …

Cancer is a complex disease involving alterations of multiple processes, with both genetic
and epigenetic features contributing as core factors to the disease. In recent years, it has …

Many studies show that daily consumption of high-fiber diet reduces the risk of developing
kidney stones, inflammatory disease, colon cancer and other malignancies, obesity, type II …

Highlights•Breast cancer is the most frequently diagnosed cancer in women.•Aberrant
expression of HATs and HDACs has been reported in breast cancer.•Epigenetic therapy is …

It is now well recognized that mutations, deregulated expression, and aberrant recruitment of
epigenetic readers, writers, and erasers are fundamentally important processes in the onset …

Cancer is a complex genetic and epigenetic-based disease that has developed an armada
of mechanisms to escape cell death. The deregulation of apoptosis and autophagy, which …