Hepatocellular carcinoma (HCC) is the fifth most frequent neoplasm worldwide (> 500,000
deaths/year), and in some areas of the world it represents the primary cause of cancer …

Staging systems are key to predict the prognosis of patients with cancer, to stratify the
patients according to prognostic variables in the setting of clinical trials, to allow the …

Materials and Methods Twenty-six resected cases of nodules from 23 patients with chronic
hepatitis or cirrhosis caused by hepatitis B or Abbreviations: GPC3, glypican-3; GS …

Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with multiple
genetic aberrations. Several molecular pathways involved in the regulation of proliferation …

OBJECTIVE. The purpose of this article is to review the use of gadolinium-ethoxybenzyl-
diethylenetriamine pentaacetic acid (gadoxetate disodium [Gd-EOB-DTPA]) in the cirrhotic …

Context.—There is increasing evidence to support a multistep model of the process of
human hepatocarcinogenesis. Precursor lesions are characterized by the appearance of …

Primary neoplasms of the liver are composed of cells that resemble the normal constituent
cells of the liver. Hepatocellular carcinoma, in which the tumor cells resemble hepatocytes …

Hepatocellular carcinoma (HCC) is characterized as a highly chemoresistant cancer with no
effective systemic therapy. Despite surgical or locoregional therapies, prognosis remains …

Hepatocellular cancer (HCC) is the fifth most common solid tumor worldwide, accounting for
500,000 new cases annually. Although less common in the United States, HCC is expected …

Abstract Hepatitis B virus X (HBx) protein is suspected to participate in oncogenesis during
chronic hepatitis B progression. Transforming growth factor β (TGF‐β) signaling involves …