Genomics is affecting all areas of medicine. In transfusion medicine, DNA-based genotyping
is being used as an alternative to serological antibody-based methods to determine blood …

Red blood cell (RBC) transfusion is one of the most frequently performed clinical procedures
and therapies to improve tissue oxygen delivery in hospitalized patients worldwide …

Coronavirus disease 2019 (COVID-19) exhibits a very wide spectrum of severity. This
strongly suggests that host factors influence outcomes. While acquired comorbidities—such …

Background There are more than 300 known red blood cell (RBC) antigens and 33 platelet
antigens that differ between individuals. Sensitisation to antigens is a serious complication …

RH genes are highly polymorphic and encode the most complex of the 35 human blood
group systems. This genetic diversity contributes to Rh alloimmunization in patients with …

In the era of blood group genomics, reference collections of complete and fully resolved
blood group gene alleles have gained high importance. For most blood groups, however …

Genetic determinants underlying most human blood groups are now clarified but variation in
expression levels remains largely unexplored. By developing a bioinformatics pipeline …

BACKGROUND Genotyping has expanded the number red blood cell (RBC) and platelet
(PLT) antigens that can readily be typed, but often represents an additional testing cost. The …

Importance McLeod syndrome, encoded by the geneXK, is a rare and progressive disease
that shares important similarities with Huntington disease but has widely varied neurologic …

Objective: This work proposes a review of the antibodies which have been associated with
variant RHD and RHCE alleles, except null alleles. Background: The data on this topic is …