Targeted Degradation of Intracellular Proteins using Ubiquitin Variant Induced Proximity

B Aminu - 2024 - atrium.lib.uoguelph.ca
Eukaryotic cells rely on proteasomal degradation mechanisms to maintain protein
homeostasis, quantity, and quality, essential for regulating various biological processes. A …

Exosomal AFAP1-AS1 promotes the growth, metastasis, and glycolysis of pituitary adenoma by preventing HuR degradation

H Tang, D Zhu, W Li, G Zhang, H Zhang, Q Peng - 2024 - researchsquare.com
Background Exosomal long noncoding RNAs (lncRNAs), which are highly concentrated in
tumor-derived exosomes, play a crucial role in modulating cellular behaviors such as cell …