Exploring the Mechanism and Suggesting Combination Therapies for HDAC Inhibitors in Androgen Receptor-Null Prostate Cancer Using Multivariate Statistical …

Z Rana, RJ Rosengren… - Bioinformatics and Biology …, 2022 - journals.sagepub.com
Previously, we showed that novel histone deacetylase (HDAC) inhibitors, N 1-hydroxy-N 8-
(4-(pyridine-2-carbothioamido) phenyl) octanediamide (Jazz90) and [chlorido (η5 …

Inhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a …

N Shrestha, AR Bland, RL Bower, RJ Rosengren… - … of Pharmacology and …, 2020 - ASPET
Anaplastic lymphoma kinase (ALK)-positive non–small-cell lung cancer most commonly
arises through EML4 (Echinoderm Microtuble Like 4)-ALK chromosomal fusion. We have …

[PDF][PDF] Combination of ALK and MEK inhibitors for the treatment of ALK-positive non-small cell lung cancer

N Shrestha - 2020 - ourarchive.otago.ac.nz
Anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) most
commonly arises through Echinoderm microtubule-associated protein like 4 (EML4)-ALK …