The development of therapeutic approaches for the induction of robust, long-lasting and
antigen-specific immune tolerance remains an important unmet clinical need for the …

Background Autoimmune hepatitis (AIH) varies significantly in incidence and prevalence
across countries and regions. We aimed to examine global, regional, and national trends in …

Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting
more commonly women than men. The most frequent forms are Graves' Disease (GD) and …

Immune responses are directed by the complex interactions of different cell types, including
T cells and Natural Killer (NK) cells, with a key type of interaction being the formation of …

Autoimmune diseases (ADs) are one of the groups of chronic illnesses that impose a
significant burden of disease and health costs worldwide. Age is a crucial risk factor for the …

Objective Variations in prevalence and incidence of systemic lupus erythematosus (SLE)
within a geographically defined area of central Sweden over a time period of 14 years were …

Graves' disease (GD) is the commonest cause of hyperthyroidism and has a strong female
preponderance. Everyday clinical practice suggests strong aggregation within families and …

The COVID-19 pandemic and other large-scale infectious disease outbreaks, such as
cholera, measles, and mpox (formerly known as monkeypox), are part of a global pattern of …

The presence of autoantibodies is a defining feature of many autoimmune diseases. The
number of unique autoantibody clones is conceivably limited by immune tolerance …

The high prevalence and rising incidence of autoimmune diseases have become a
prominent public health issue. Autoimmune disorders result from the immune system …