This review projects the prospects and issues faced by solid lipid nanoparticles (SLNs) in
current scenarios, specially related to its clinical implementation and effectiveness. We re …

Membrane transporters play a key role in the absorption, distribution, clearance, elimination,
and transport of drugs. Understanding the drug properties and structure activity relationships …

The Culex mosquito-transmitted dengue virus (DENV) under genus Flavivirus, a member of
Flaviviridae family, cause dengue fever worldwide also in many parts of India. At present …

We report the development of a chemical modification method of general applicability to
polyphenols, which increases solubility to influence absorption. Glucosyl groups were …

The aim of the present study was to develop optimal dissolution conditions for a BCS Class II
drug in early development. The model drug efavirenz was formulated in two dosage forms: a …

The relationship of in-silico predicted physical/chemical properties and human toxicity is
analyzed for a statistically significant sample size of chemical compounds. Results for …

In vivo pharmacokinetic simulations and virtual bioequivalence (BE) evaluation of cilostazol
have not yet been described for humans. Here, we successfully developed a physiologically …

Purpose: Resveratrol (RV), a promising anti-cancer candidate, is limited in application for its
poor bioavailability. However, the better bioavailability has been found in some RV …

Apocynin, a potent inhibitor of NADPH-oxidase, was widely studied for activities in diseases
such as inflammation-mediated disorders, asthma and cardiovascular diseases. In our …

There is a possibility of in-situ physicochemical interactions between concomitantly
administered drugs. This study aimed to investigate such physicochemical interactions …