[PDF][PDF] Adaptive immunity to SARS-CoV-2 and COVID-19

A Sette, S Crotty - Cell, 2021 - cell.com
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …

Single-cell immunology of SARS-CoV-2 infection

Y Tian, LN Carpp, HER Miller, M Zager… - Nature …, 2022 - nature.com
Gaining a better understanding of the immune cell subsets and molecular factors associated
with protective or pathological immunity against severe acute respiratory syndrome …

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

JM Dan, J Mateus, Y Kato, KM Hastie, ED Yu, CE Faliti… - Science, 2021 - science.org
INTRODUCTION Immunological memory is the basis for durable protective immunity after
infections or vaccinations. Duration of immunological memory after severe acute respiratory …

Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

AK Wheatley, JA Juno, JJ Wang, KJ Selva… - Nature …, 2021 - nature.com
The durability of infection-induced SARS-CoV-2 immunity has major implications for
reinfection and vaccine development. Here, we show a comprehensive profile of antibody, B …

SARS-CoV-2–specific CD8+ T cell responses in convalescent COVID-19 individuals

H Kared, AD Redd, EM Bloch, TS Bonny… - The Journal of …, 2021 - Am Soc Clin Investig
Characterization of the T cell response in individuals who recover from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is critical to understanding its …

Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8+ T cells

A Kusnadi, C Ramírez-Suástegui, V Fajardo… - Science …, 2021 - science.org
The molecular properties of CD8+ T cells that respond to SARS-CoV-2 infection are not fully
known. Here, we report on the single-cell transcriptomes of> 80,000 virus-reactive CD8+ T …

[PDF][PDF] Alterations in T and B cell function persist in convalescent COVID-19 patients

HA Shuwa, TN Shaw, SB Knight, K Wemyss… - Med, 2021 - cell.com
Background Emerging studies indicate that some coronavirus disease 2019 (COVID-19)
patients suffer from persistent symptoms, including breathlessness and chronic fatigue; …

[HTML][HTML] Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection

C Riou, E Du Bruyn, C Stek… - The Journal of …, 2021 - Am Soc Clin Investig
JCI - Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of
HIV-1 and tuberculosis coinfection Go to JCI Insight About Editors Consulting Editors For authors …

[HTML][HTML] T-helper cell subset response is a determining factor in COVID-19 progression

FJ Gil-Etayo, P Suàrez-Fernández… - Frontiers in cellular …, 2021 - frontiersin.org
The immune response type organized against viral infection is determinant in the prognosis
of some infections. This work has aimed to study Th polarization in acute COVID-19 and its …

The role of Th17 response in COVID-19

D Martonik, A Parfieniuk-Kowerda, M Rogalska… - Cells, 2021 - mdpi.com
COVID-19 is an acute infectious disease of the respiratory system caused by infection with
the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus 2). Transmission …