Drug addiction is a chronic and relapsing brain disorder characterized by compulsive drug
seeking and continued drug use despite adverse consequences. The high prevalence and …

Opioids are substances derived from opium (natural opioids). In its raw state, opium is a
gummy latex extracted from Papaver somniferum. The use of opioids and their negative …

Background and Purpose Adolescents are regularly exposed to∆ 9‐tetrahydrocannabinol
(THC) via smoking and, more recently, vaping cannabis extracts. Growing legalization of …

Addiction is a chronic and relapsing brain disorder characterized by compulsive seeking
despite adverse consequences. There are both heritable and epigenetic mechanisms …

The over-prescription of opioid analgesics is a growing problem in the field of addiction,
which has reached epidemic-like proportions in North America. Over the past decade …

Background This study aimed to investigate the mechanism of miR-29a-3p in regulating
endometrial cancer (EC) progression. Methods A total of 72 EC patients were enrolled. EC …

Introduction Rates of relapse to drug use during abstinence are among the highest for opioid
use disorder (OUD). In preclinical studies, reinstatement to drug-seeking has been …

Healthy persons hold a very complex system for controlling energy homeostasis. The system
functions on the interconnected way between the nutritional, endocrine, neural, and …

Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is
hampered by perseverant drug cravings that may persist for months after cessation of drug …

This paper is the forty-second consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …