Importance Lung cancer is the leading cause of cancer-related death in the US. Objective To
review the evidence on screening for lung cancer with low-dose computed tomography …

Lung cancer is the leading cause of cancer-related death worldwide. However, lung cancer
incidence and mortality rates differ substantially across the world, reflecting varying patterns …

Lung cancer is the leading cause of mortality and person-years of life lost from cancer
among US men and women. Early detection has been shown to be associated with reduced …

In the past decade, the introduction of molecularly targeted agents and immune-checkpoint
inhibitors has led to improved survival outcomes for patients with advanced-stage lung …

Importance The US Preventive Services Task Force (USPSTF) is updating its 2013 lung
cancer screening guidelines, which recommend annual screening for adults aged 55 …

Randomised controlled trials, including the National Lung Screening Trial (NLST) and the
NELSON trial, have shown reduced mortality with lung cancer screening with low-dose CT …

In the United States, lung cancer is the second most common diagnosed cancer and the
leading cause of cancer-related death. Although tobacco smoking is the major risk factor …

Background There are limited data from randomized trials regarding whether volume-based,
low-dose computed tomographic (CT) screening can reduce lung-cancer mortality among …

Background Lung cancer is the leading cause of cancer death worldwide. Data on the
effectiveness of one-off low-dose CT (LDCT) in reducing lung cancer mortality and all-cause …

Background Lung cancer is a major health problem. CT lung screening can reduce lung
cancer mortality through early diagnosis by at least 20%. Screening high-risk individuals is …