[HTML][HTML] Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

[HTML][HTML] Data capture and sharing in the COVID-19 pandemic: a cause for concern

L Dron, V Kalatharan, A Gupta, J Haggstrom… - The Lancet Digital …, 2022 - thelancet.com
Routine health care and research have been profoundly influenced by digital-health
technologies. These technologies range from primary data collection in electronic health …

[HTML][HTML] Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster …

AB Andoh, AA Francis, AA Abdulkarim… - The Lancet, 2022 - thelancet.com
Background Surgical site infection (SSI) remains the most common complication of surgery
around the world. WHO does not make recommendations for changing gloves and …

Optimizing clinical nutrition research: the role of adaptive and pragmatic trials

CE Orsso, KL Ford, N Kiss, EB Trujillo… - European journal of …, 2023 - nature.com
Evidence-based nutritional recommendations address the health impact of suboptimal
nutritional status. Efficacy randomized controlled trials (RCTs) have traditionally been the …

[HTML][HTML] Breaking the mold with RNA—a “RNAissance” of life science

CH Jones, JR Androsavich, N So, MP Jenkins… - NPJ Genomic …, 2024 - nature.com
In the past decade, RNA therapeutics have gone from being a promising concept to one of
the most exciting frontiers in healthcare and pharmaceuticals. The field is now entering what …

[HTML][HTML] Perfil clínico e fatores associados ao óbito de pacientes COVID-19 nos primeiros meses da pandemia

L Pontes, MTR Danski, SMN Piubello, JFG Pereira… - Escola Anna …, 2021 - SciELO Brasil
Objetivo analisar as características individuais, clínicas e os fatores associados à
mortalidade de pacientes com COVID-19, em hospital público do estado do Paraná, Brasil …

[HTML][HTML] New clinical trial design in precision medicine: discovery, development and direction

XP Duan, BD Qin, XD Jiao, K Liu, Z Wang… - Signal Transduction and …, 2024 - nature.com
In the era of precision medicine, it has been increasingly recognized that individuals with a
certain disease are complex and different from each other. Due to the underestimation of the …

[HTML][HTML] Urgently seeking efficiency and sustainability of clinical trials in global health

JJH Park, RF Grais, M Taljaard… - The Lancet Global …, 2021 - thelancet.com
This paper shows the scale of global health research and the context in which we frame the
subsequent papers in the Series. In this Series paper, we provide a historical perspective on …

[HTML][HTML] Sustained rise in retractions in the life sciences literature during the pandemic years 2020 and 2021

NSL Yeo-Teh, BL Tang - Publications, 2022 - mdpi.com
The COVID-19 pandemic has been devastating to all human endeavors, and scientific
research has not been spared. We queried how the retraction of publications might have …

[HTML][HTML] Leveraging the HIV response to strengthen pandemic preparedness

C Collins, MT Isbell, QA Karim, AH Sohn… - PLOS Global Public …, 2023 - journals.plos.org
The COVID-19 pandemic and the expectation of future pandemic threats have generated a
global dialogue on strengthening pandemic preparedness and response (PPR). Thus far …