It has been argued that, as evidence-based medicine emerged in the 1990s, healthcare
practitioners are required to partake in more intricate and elaborate cognitive processes. As …

Employment can provide numerous benefits to quality of life, mental health, and social
inclusion, which can be particularly important for people with disabilities. In a pilot study, the …

With billions of dollars in research and development (R&D) funding continuing to be
invested, the novel coronavirus disease 2019 (COVID-19) has become into a singular focus …

Extract From the influenza pandemic of 1918–1919 to the most recent COVID-19 pandemic,
respiratory infections remain a leading cause of mortality worldwide [1, 2]. Concurrently, the …

In recent times, there have been calls from within the developing nations for increased
ownership by governmental research bodies and universities of the priority research setting …

Objectives Improving the targeted use of drug regimens requires robust real-world evidence
(RWE) to address the uncertainties that remain regarding their real-world performance …

In trials of infectious disease interventions, rare outcomes and unpredictable spatiotemporal
variation can introduce bias, reduce statistical power, and prevent conclusive inferences …

In clinical drug development, two fundamental questions remain unanswered: what is the
success rate of drugs in clinical trial? how does such rate change over time? Herein, a …

Data aggregation, also known as meta analysis, is widely used to combine knowledge on
parameters shared in common (eg, average treatment effect) between multiple studies. In …

Randomised controlled trials (RCTs) play an important role in multiple sclerosis (MS)
research, ensuring that new interventions are safe and efficacious before their introduction …