Red blood cell distribution width (RDW) correlates to the anatomical location of colorectal cancer. implications for clinical use

A Fancellu, A Zinellu, AA Mangoni, A Popova… - Journal of …, 2022 - Springer
Purpose The pathological, clinical, and therapeutic features of colorectal cancer (CRC)
depend on its anatomical localization. We investigated possible associations between the …

Node-negative colon cancer: histological, molecular, and stromal features predicting disease recurrence

MTA Strous, RLA van der Linden, ALHM Gubbels… - Molecular …, 2023 - Springer
Background Within the group of node-negative colon cancer patients, presumed to have a
good prognosis, a significant percentage of patients develops cancer-recurrence. Current …

[HTML][HTML] Relationship between mismatch repair protein, RAS, BRAF, PIK3CA gene expression and clinicopathological characteristics in elderly colorectal cancer …

JZ Fan, GF Wang, XB Cheng, ZH Dong… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Colorectal cancer (CRC) is common in elderly patients. Mismatch repair
(MMR) protein deletion is one of the causes of CRC. The RAS (KRAS/NRAS), BRAF, and …

[HTML][HTML] Cholangiocarcinoma: the role of genetic and epigenetic factors; current and prospective treatment with checkpoint inhibitors and immunotherapy

P Sarantis, ED Tzanetatou, E Ioakeimidou… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Cholangiocarcinoma (CCA) represents 3% of all gastrointestinal cancers worldwide
and is the second most common primary liver tumor after hepatocellular carcinoma. CCA is …

[HTML][HTML] Combined assessment of the TNM stage and BRAF mutational status at diagnosis in sporadic colorectal cancer patients

JM Sayagués, S Del Carmen, MDM Abad… - Oncotarget, 2018 - ncbi.nlm.nih.gov
The prognostic impact of KRAS mutations and other KRAS-related and non-related genes
such as BRAF, NRAS and TP53, on sporadic colorectal cancer (sCRC) remain controversial …

Clinicopathological features and predictive factors for colorectal cancer outcome in the Kingdom of Saudi Arabia

A Aldiab, KA Al Khayal, OA Al Obaid, A Alsheikh… - Oncology, 2017 - karger.com
Abstract Background/Aims: Colorectal cancer (CRC) is the most frequent cancer and a
leading cause of cancer death in the Kingdom of Saudi Arabia (KSA). To date, no …

Placental ras regulates inflammation associated with maternal obesity

S Liong, G Barker, M Lappas - Mediators of inflammation, 2018 - Wiley Online Library
Heightened placental inflammation and dysfunction are commonly associated in pregnant
obese women compared to their pregnant lean counterparts. The small GTPase superfamily …

Deficient mismatch repair and RAS mutation in colorectal carcinoma patients: a retrospective study in Eastern China

X Zhang, W Ran, J Wu, H Li, H Liu, L Wang, Y Xiao… - PeerJ, 2018 - peerj.com
Objectives To investigate the frequency and prognostic role of deficient mismatch repair
(dMMR) and RAS mutation in Chinese patients with colorectal carcinoma. Methods Clinical …

[HTML][HTML] Identification of biomarkers in colon cancer based on bioinformatic analysis

Y Zhu, L Sun, J Yu, Y Xiang, M Shen… - Translational Cancer …, 2020 - ncbi.nlm.nih.gov
Background Colon cancer is one of the most common cancers in the world. Targeting
biomarkers is helpful for the diagnosis and treatment of colon cancer. This study aimed to …

Defining the optimal use of ablation for metastatic colorectal cancer to the liver without high-level evidence

R Diaz-Nieto, S Fenwick, H Malik, G Poston - Current treatment options in …, 2017 - Springer
Opinion statement The role of physical interventions (surgical resection and
surgical/radiological ablation) for liver metastases of colorectal cancer has changed …