[HTML][HTML] SARS-CoV-2 and the DNA damage response

RJ Grand - Journal of General Virology, 2023 - microbiologyresearch.org
The recent coronavirus disease 2019 (COVID-19) pandemic was caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is characterized by …

Exposure estimation and neurotoxicity inhibition of dioxins in sensitive populations near domestic waste incineration plant through adverse outcome pathway

Q Li, Y Li, Q Pu, H Yang, M Du, X Li, Y Li, X Li - Journal of Hazardous …, 2024 - Elsevier
The neurotoxicity induced by dioxins has been recognized as a serious concern to sensitive
population living near waste incineration plants. However, investigating the intracellular …

[HTML][HTML] Synthesis and in silico inhibitory action studies of azo-anchored imidazo[4,5-b]indole scaffolds against the COVID-19 main protease (Mpro)

D Geedkar, A Kumar, P Sharma - Scientific Reports, 2024 - nature.com
The present work elicits a novel approach to combating COVID-19 by synthesizing a series
of azo-anchored 3, 4-dihydroimidazo [4, 5-b] indole derivatives. The envisaged methodology …

[HTML][HTML] Harnessing Brazilian biodiversity database: identification of flavonoids as potential inhibitors of SARS-CoV-2 main protease using computational approaches …

JAP da Rocha, RA da Costa, ASS da Costa… - Frontiers in …, 2024 - frontiersin.org
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) is the etiological agent
responsible for the global outbreak of COVID-19 (Coronavirus Disease 2019). The main …

[HTML][HTML] Dual anticancer and antibacterial activity of fluorescent naphthoimidazolium salts

DN Tran, TTH Hoang, S Nandanwar, VTTX Ho… - RSC …, 2023 - pubs.rsc.org
Cancer has emerged as a significant global health challenge, ranking as the second leading
cause of death worldwide. Moreover, cancer patients frequently experience compromised …

CBPDdb: a curated database of compounds derived from Coumarin–Benzothiazole–Pyrazole

S Rampogu, MR Shaik, M Khan, M Khan, TH Oh… - Database, 2023 - academic.oup.com
The present article describes the building of a small-molecule web server, CBPDdb,
employing R-shiny. For the generation of the web server, three compounds were chosen …