Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …

Traumatic brain injury (TBI) remains a major cause of death and disability worldwide.
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …

The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

Epidemiological evidence demonstrates a link between air pollution exposure and the onset
and progression of cognitive impairment and Alzheimer's disease (AD). However, current …

The glymphatic system is a perivascular fluid clearance system, most active during sleep,
considered important for clearing the brain of waste products and toxins. Glymphatic failure …

Purpose Glymphatic system dysfunction has been reported in animal models of traumatic
brain injury (TBI). This study aimed to evaluate the activity of the human glymphatic system …

The glymphatic system is a unique pathway that utilises end-feet Aquaporin 4 (AQP4)
channels within perivascular astrocytes, which is believed to cause cerebrospinal fluid …

Objective The glymphatic system is thought to be responsible for waste clearance in the
brain. As it is primarily active during sleep, different components of sleep, subjective sleep …

The complex and dynamic system of fluid flow through the perivascular and interstitial
spaces of the CNS has new-found implications for neurological diseases. CSF movement …

Blood-based protein biomarkers have revolutionized several fields of medicine by enabling
molecular level diagnosis, as well as monitoring disease progression and treatment efficacy …