G Li, E De Clercq - Microbiology and Molecular Biology Reviews, 2016 - Am Soc Microbiol
The HIV genome encodes a small number of viral proteins (ie, 16), invariably establishing cooperative associations among HIV proteins and between HIV and host proteins, to invade …
G Li, S Piampongsant, NR Faria, A Voet… - Retrovirology, 2015 - Springer
Background The HIV pandemic is characterized by extensive genetic variability, which has challenged the development of HIV drugs and vaccines. Although HIV genomes have been …
M Miao, E De Clercq, G Li - Microorganisms, 2022 - mdpi.com
Despite the active development of SARS-CoV-2 surveillance methods (eg, Nextstrain, GISAID, Pangolin), the global emergence of various SARS-CoV-2 viral lineages that …
CK Sruthi, M Prakash - PloS one, 2018 - journals.plos.org
Amino acid mutations in proteins are random and those mutations which are beneficial or neutral survive during the course of evolution. Conservation or co-evolution analyses are …
The HIV-1 Env spike is the main protein complex that facilitates HIV-1 entry into CD4+ host cells. HIV-1 entry is a multistep process that is not yet completely understood. This process …
Adeno-associated virus (AAV) is a promising gene therapy vector because of its efficient gene delivery and relatively mild immunogenicity. To improve delivery target specificity …
M Miao, E De Clercq, G Li - 2022 - researchgate.net
Despite the active development of SARS-CoV-2 surveillance methods (eg, Nextstrain, GISAID, Pangolin), the global emergence of various SARS-CoV-2 viral lineages that …
For decades, immunologists and virologists have worked somewhat independently trying to understand AIDS disease progression for the benefit of improved patient care. Their efforts …
Die derzeitigen Leitlinien zur antiretroviralen Therapie von HIV Patienten empfehlen die Integrase-Inhibitoren als potente Kombinationspartner mit einer breiten Wirksamkeit gegen …