Understanding how traumatic stress affects typical brain development during adolescence is
critical to elucidate underlying mechanisms related to both maladaptive functioning and …

A rapidly growing number of studies on autism spectrum disorder (ASD) have used resting‐
state fMRI to identify alterations of functional connectivity, with the hope of identifying clinical …

Heterogeneity is an important concept in psychiatric research and science more broadly. It
negatively impacts effect size estimates under case–control paradigms, and it exposes …

Normative modeling aims to quantify the degree to which an individual's brain deviates from
a reference sample with respect to one or more variables, which can be used as a potential …

Brain scans acquired across large, age-diverse cohorts have facilitated recent progress in
establishing normative brain aging charts. Here, we ask the critical question of whether …

Schizophrenia is a debilitating neuropsychiatric disorder whose underlying correlates
remain unclear despite decades of neuroimaging investigation. One contentious topic …

The number of individuals affected by traumatic brain injury (TBI) is growing globally. TBIs
may cause a range of physical, cognitive, and psychiatric deficits that can negatively impact …

Modelling population reference curves or normative modelling is increasingly used with the
advent of large neuroimaging studies. In this paper we assess the performance of fitting …

Previous structural and functional neuroimaging studies have implicated distributed brain
regions and networks in depression. However, there are no robust imaging biomarkers that …

Background The heterogeneity of the clinical symptoms and presumptive neural pathologies
has stunted progress toward identifying reproducible biomarkers and limited therapeutic …