[HTML][HTML] Compartmentalized regulation of lipid signaling in oxidative stress and inflammation: Plasmalogens, oxidized lipids and ferroptosis as new paradigms of …

AM Astudillo, MA Balboa, J Balsinde - Progress in Lipid Research, 2023 - Elsevier
Perturbations in lipid homeostasis combined with conditions favoring oxidative stress
constitute a hallmark of the inflammatory response. In this review we focus on the most …

Selectivity of phospholipid hydrolysis by phospholipase A2 enzymes in activated cells leading to polyunsaturated fatty acid mobilization

AM Astudillo, MA Balboa, J Balsinde - … (BBA)-Molecular and Cell Biology of …, 2019 - Elsevier
Phospholipase A 2 s are enzymes that hydrolyze the fatty acid at the sn-2 position of the
glycerol backbone of membrane glycerophospholipids. Given the asymmetric distribution of …

PLA2G6 guards placental trophoblasts against ferroptotic injury

O Beharier, VA Tyurin, JP Goff… - Proceedings of the …, 2020 - National Acad Sciences
The recently identified ferroptotic cell death is characterized by excessive accumulation of
hydroperoxy-arachidonoyl (C20: 4)-or adrenoyl (C22: 4)-phosphatidylethanolamine (Hp …

Chronic exposure to polyvinyl chloride microplastics induces liver injury and gut microbiota dysbiosis based on the integration of liver transcriptome profiles and full …

X Chen, J Zhuang, Q Chen, L Xu, X Yue… - Science of the Total …, 2022 - Elsevier
Microplastics (MPs) have become harmful environmental pollutants, and their potential
toxicity to organisms has attracted extensive attention. However, the effects of polyvinyl …

Polystyrene nanoplastic induces oxidative stress, immune defense, and glycometabolism change in Daphnia pulex: Application of transcriptome profiling in risk …

Z Liu, Y Li, E Pérez, Q Jiang, Q Chen, Y Jiao… - Journal of Hazardous …, 2021 - Elsevier
Aquatic environments are generally contaminated with nanoplastic material. As a result,
molecular mechanisms for sensitive species like Daphnia are needed, given that …

Anti‐inflammatory properties of cerium oxide nanoparticles

SM Hirst, AS Karakoti, RD Tyler, N Sriranganathan… - Small, 2009 - Wiley Online Library
The valence and oxygen defect properties of cerium oxide nanoparticles (nanoceria)
suggest that they may act as auto‐regenerative free radical scavengers. Overproduction of …

Role of oxidative stress in ocular diseases: a balancing act

DY Shu, S Chaudhary, KS Cho, A Lennikov, WP Miller… - Metabolites, 2023 - mdpi.com
Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

Dynamics of arachidonic acid mobilization by inflammatory cells

AM Astudillo, D Balgoma, MA Balboa… - Biochimica et Biophysica …, 2012 - Elsevier
The development of mass spectrometry-based techniques is opening new insights into the
understanding of arachidonic acid (AA) metabolism. AA incorporation, remodeling and …

Role of retinal glial cells in neurotransmitter uptake and metabolism

A Bringmann, T Pannicke, B Biedermann… - Neurochemistry …, 2009 - Elsevier
In addition to photoreceptors and neurons, glial cells (in particular Müller cells) contribute to
the removal and metabolization of neurotransmitters in the neural retina. This review …

Mechanisms of glycerophospholipid homeostasis in mammalian cells

M Hermansson, K Hokynar, P Somerharju - Progress in lipid research, 2011 - Elsevier
The membranes of mammalian cells contain hundreds of different phospholipid species, a
variety of glycolipids and cholesterol. While the reasons for such compositional diversity are …