Atherosclerosis is the most common cardiovascular disease and is the number one cause of
death worldwide. Today, atherosclerosis is a multifactorial chronic inflammatory disease with …

Our bodies are inhabited by trillions of microorganisms. The host immune system constantly
interacts with the microbiota in barrier organs, including the intestines. Over decades …

Background Tumour necrosis factor superfamily protein 14 (TNFSF14), also called LIGHT, is
an important regulator of immunological and fibrosis diseases. However, its specific …

Background The inflammatory response to cerebral ischemia is complex; however, most
clinical studies of stroke outcome focus on a few selected proteins. We, therefore, aimed to …

Background Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease
affecting multiple organs and tissues with high cellular heterogeneity. CD8+ T cell activity is …

Understanding the regulatory mechanisms facilitating hematopoietic stem cell (HSC)
specification during embryogenesis is important for the generation of HSCs in vitro …

The intricate immune mechanisms governing mucosal healing following intestinal damage
induced by cytotoxic drugs remain poorly understood. The goal of this study was to …

The herpesvirus entry mediator (HVEM) and its ligand LIGHT play crucial roles in immune
system regulation, including T-cell proliferation, B-cell differentiation, and immunoglobulin …

Psoriasis (PS) and atopic dermatitis (AD) are common skin inflammatory diseases
characterized by hyper-responsive keratinocytes. Although, some cytokines have been …

Introduction Untreated gout is characterised by monosodium urate (MSU) crystal
accumulation responsible for recurrent flares that are commonly separated by asymptomatic …