[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

Current knowledge and future perspectives of exosomes as nanocarriers in diagnosis and treatment of diseases

Z Zou, H Li, G Xu, Y Hu, W Zhang… - International Journal of …, 2023 - Taylor & Francis
Exosomes, as natural nanocarriers, characterized with low immunogenicity, non-cytotoxicity
and targeted delivery capability, which have advantages over synthetic nanocarriers …

Extracellular vesicles linking inflammation, cancer and thrombotic risks

S Beck, B Hochreiter, JA Schmid - Frontiers in cell and developmental …, 2022 - frontiersin.org
Extracellular vesicles (EVs) being defined as lipid-bilayer encircled particles are released by
almost all known mammalian cell types and represent a heterogenous set of cell fragments …

[HTML][HTML] CRISPR/Cas9-engineered mesenchymal stromal/stem cells and their extracellular vesicles: A new approach to overcoming cell therapy limitations

A Hazrati, K Malekpour, S Soudi… - Biomedicine & …, 2022 - Elsevier
Cell therapy is one of the newest therapeutic approaches for treating tissue destruction
diseases and replacing damaged parts in defective tissues. Among different cells …

Interrelationship between COVID-19 and coagulopathy: pathophysiological and clinical evidence

B Ragnoli, B Da Re, A Galantino, S Kette… - International Journal of …, 2023 - mdpi.com
Since the first description of COVID-19 infection, among clinical manifestations of the
disease, including fever, dyspnea, cough, and fatigue, it was observed a high incidence of …

Exosome derived from stem cell: A promising therapeutics for wound healing

H Lv, H Liu, T Sun, H Wang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
A wound occurs when the epidermis and dermis of the skin are damaged internally and
externally. The traditional wound healing method is unsatisfactory, which will prolong the …

Roles of exosomes and exosome-derived miRNAs in pulmonary fibrosis

Y Yang, H Huang, Y Li - Frontiers in Pharmacology, 2022 - frontiersin.org
Pulmonary fibrosis is a chronic, progressive fibrosing interstitial lung disease of unknown
etiology that leads rapidly to death. It is characterized by the replacement of healthy tissue …

Potential therapeutic applications of extracellular vesicles in the immunopathogenesis of COVID-19

M Motallebnezhad, M Omraninava, HEG Ghaleh… - … -Research and Practice, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the cause of
coronavirus disease 2019 (COVID-19) which has emerged as a global health crisis …

Advancements in engineered mesenchymal stem cell exosomes for chronic lung disease treatment

Z Zhai, T Cui, J Chen, X Mao, T Zhang - Journal of Translational Medicine, 2023 - Springer
Chronic lung diseases include an array of conditions that impact airways and lung
structures, leading to considerable societal burdens. Mesenchymal stem cells (MSCs) and …

MiRNA and exosomal miRNA as new biomarkers useful to phenotyping severe asthma

P Soccio, G Moriondo, D Lacedonia, P Tondo… - Biomolecules, 2023 - mdpi.com
Severe asthma (SA) is a chronic inflammatory disease of the airways. Due to the extreme
heterogeneity of symptoms, new biomarkers are currently needed. MiRNAs are non-coding …