The role of obesity in type 2 diabetes mellitus—An overview

P Chandrasekaran, R Weiskirchen - International Journal of Molecular …, 2024 - mdpi.com
Obesity or excessive weight gain is identified as the most important and significant risk factor
in the development and progression of type 2 diabetes mellitus (DM) in all age groups. It has …

PPAR-γ partial agonists in disease-fate decision with special reference to cancer

S Ballav, B Biswas, VK Sahu, A Ranjan, S Basu - Cells, 2022 - mdpi.com
Peroxisome proliferator-activated receptor-γ (PPAR-γ) has emerged as one of the most
extensively studied transcription factors since its discovery in 1990, highlighting its …

Endocannabinoid-binding receptors as drug targets

M Gómez-Cañas, C Rodríguez-Cueto, V Satta… - … Signaling: Methods and …, 2022 - Springer
Cannabis plant has been used from ancient times with therapeutic purposes for treating
human pathologies, but the identification of the cellular and molecular mechanisms …

Assessing the in vitro and in vivo performance of L-carnitine-loaded nanoparticles in combating obesity

B Uner, AD Ergin, IA Ansari, MS Macit-Celebi… - Molecules, 2023 - mdpi.com
Addressing obesity is a critical health concern of the century, necessitating urgent attention.
L-carnitine (LC), an essential water-soluble compound, plays a pivotal role in lipid …

Influence of body mass index on severity of rotator cuff tears

PW Weng, WP Chang - Journal of Shoulder and Elbow Surgery, 2024 - Elsevier
Background Research on the relationship between obesity and rotator cuff tears (RCTs) has
been limited to the impact of obesity on the results of arthroscopic repair of RCTs; thus, a …

Consumption of saturated fatty acids‐rich lard benefits recovery of experimental arthritis by activating PPAR‐γ

R Wang, CL Ji, DD Feng, YJ Wu, Y Li… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope This study investigates the impacts of lard and related fatty acids intake on
rheumatoid arthritis (RA) animal models. Method and results Collagen‐induced arthritis …

The anti-adiposity mechanisms of ampelopsin and vine tea extract in high fat diet and alcohol-induced fatty liver mouse models

J Wu, K Miyasaka, W Yamada, S Takeda, N Shimizu… - Molecules, 2022 - mdpi.com
Ampelopsis grossedentata (AG) is an ancient medicinal plant that is mainly distributed and
used in southwest China. It exerts therapeutic effects, such as antioxidant, anti-diabetic, and …

The potential effect of green synthesis of zinc oxide nanostructures using Cyperus Rotundus grass extracts on the genes associated with obesity in the 3T3-L1 cell line

FS Alatawi - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Cyperus rotundus is widely used in traditional medicine, and studies have revealed that it
contains pharmacological effects. However, the chemical composition of the plant and the …

Deciphering the interaction between Twist1 and PPARγ during adipocyte differentiation

L Sun, S Ji, X Xie, L Si, S Liu, Y Lin, Y Wang… - Cell Death & …, 2023 - nature.com
Obesity, a worldwide epidemic in recent years, is mainly due to the uncontrolled
development of adipose tissues, which includes adipocyte hypertrophy and hyperplasia …

From development to future prospects: The adipose tissue & adipose tissue organoids

EB Okumuş, ÖB Böke, SŞ Turhan, A Doğan - Life Sciences, 2024 - Elsevier
Living organisms store their energy in different forms of fats including lipid droplets,
triacylglycerols, and steryl esters. In mammals and some non-mammal species, the energy …