Altered secretion of cortisol, the primary effector of the hypothalamus–pituitary–adrenal axis,
has been proposed as a means by which traumatic experiences compromise later mental …

Bipolar disorder is a mental health disorder characterized by extreme shifts in mood, high
suicide rate, sleep problems, and dysfunction of psychological traits like self-esteem (feeling …

Adverse stressful experiences in utero can redirect fetal brain development, ultimately
leading to increased risk for psychiatric disorders. Obesity during pregnancy can have …

This review examines the role of trauma in psychiatric morbidity and analogous
psychoneurobiological changes. Trauma is a necessary criterion for Post-Traumatic Stress …

Child maltreatment rates remain unacceptably high and rates are likely to escalate as
COVID-related economic problems continue. A comprehensive and evidence-building …

Background: This systematic review with meta-analysis was carried out to study the
relationship between workplace violence and sleep problems. Methods: The PRISMA …

With this manuscript we provide an overview of the prevalence, symptoms, risk factors,
screening, support, and treatment for women with a traumatic childbirth experience or …

Blunted stress reactivity resulting from early exposure to stress during childhood and
adolescence may increase vulnerability to addiction. Early life adversity (ELA) affects brain …

Aberrations in neurodevelopmental trajectories have been implicated in the neurobiology of
several mental disorders and evidence indicates a pathophysiological and genetic overlap …

Stress is defined as a state of threatened or perceived as threatened homeostasis. The well-
tuned coordination of the stress response system is necessary for an organism to respond to …