Childhood maltreatment (CM) is an established major risk factor for a number of negative
health outcomes later in life. While epigenetic mechanisms, such as DNA methylation …

Childhood adversity is related to an increased risk for psychopathology in adulthood. Altered
regulation of stress response systems, as well as the changes in stress-immune interplay …

Farm animals routinely undergo painful husbandry procedures early in life, including
disbudding and castration in calves and goat kids, tail docking and castration in piglets and …

Functional somatic disorders (FSD) result from a complex interplay of biological,
psychological, and social factors, the combination of which varies between individuals …

Early life stress (ELS) can significantly influence biological pathways associated with
nociception, increasing vulnerability to future heightened pain sensitivity and subsequent …

Obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) are
commonly comorbid and share prominent features (eg, intrusions, safety behaviors, and …

Early-life stress, such as childhood maltreatment, is a well-known etiological factor in
psychopathology, including psychosis. Exposure to early-life stress disrupts the …

Abstract Type II Diabetes Mellitus (T2DM) is a serious public health issue, affecting the
global population, particularly those living in low‐and middle‐income countries. Worldwide …

Background Emerging epidemiological evidence indicates nature exposure could be
associated with greater health benefits among groups in lower versus higher socioeconomic …

The present study examined the effect of early life stress (ELS) on the glucocorticoid
receptor gene (NR3C1) methylation, the associations between NR3C1 methylation and …