Arousal increases neural gain via the locus coeruleus–noradrenaline system in younger adults but not in older adults

TH Lee, SG Greening, T Ueno, D Clewett… - Nature human …, 2018 - nature.com
In younger adults, arousal amplifies attentional focus to the most salient or goal-relevant
information while suppressing other information. A computational model of how the locus …

The aging motor system as a model for plastic changes of GABA-mediated intracortical inhibition and their behavioral relevance

KF Heise, M Zimerman, J Hoppe, C Gerloff… - Journal of …, 2013 - Soc Neuroscience
Since GABAA-mediated intracortical inhibition has been shown to underlie plastic changes
throughout the lifespan from development to aging, here, the aging motor system was used …

[HTML][HTML] A literature review on the neurophysiological underpinnings and cognitive effects of transcutaneous vagus nerve stimulation: challenges and future directions

L Colzato, C Beste - Journal of neurophysiology, 2020 - journals.physiology.org
Brain stimulation approaches are important to gain causal mechanistic insights into the
relevance of functional brain regions and/or neurophysiological systems for human cognitive …

A meta-analysis of the effects of aging on motor cortex neurophysiology assessed by transcranial magnetic stimulation

A Bhandari, N Radhu, F Farzan, BH Mulsant… - Clinical …, 2016 - Elsevier
Objective Transcranial magnetic stimulation (TMS) is a non-invasive tool used for studying
cortical excitability and plasticity in the human brain. This review aims to quantitatively …

Age-related neural dedifferentiation in the motor system

J Carp, J Park, A Hebrank, DC Park, TA Polk - PloS one, 2011 - journals.plos.org
Recent neuroimaging studies using multi-voxel pattern analysis (MVPA) show that
distributed patterns of brain activation elicited by different visual stimuli are less distinctive in …

Glial dysregulation in the human brain in fragile X-associated tremor/ataxia syndrome

CM Dias, B Issac, L Sun, A Lukowicz… - Proceedings of the …, 2023 - National Acad Sciences
Short trinucleotide expansions at the FMR1 locus are associated with the late-onset
condition fragile X-associated tremor/ataxia syndrome (FXTAS), which shows very different …

Standard multiscale entropy reflects neural dynamics at mismatched temporal scales: What's signal irregularity got to do with it?

JQ Kosciessa, NA Kloosterman… - PLoS computational …, 2020 - journals.plos.org
Multiscale Entropy (MSE) is used to characterize the temporal irregularity of neural time
series patterns. Due to its' presumed sensitivity to non-linear signal characteristics, MSE is …

[PDF][PDF] Neocortical inhibitory system

R Druga - Folia Biol (Praha), 2009 - pmr.cuni.cz
The neocortex contains two neuron types, excitatory (glutamatergic) pyramidal cells and
inhibitory nonpyramidal (GABAergic) cells. GABAergic, inhibitory interneurons are …

The development of human visual cortex and clinical implications

CR Siu, KM Murphy - Eye and brain, 2018 - Taylor & Francis
The primary visual cortex (V1) is the first cortical area that processes visual information.
Normal development of V1 depends on binocular vision during the critical period, and age …

Aberrant occipital dynamics differentiate HIV-infected patients with and without cognitive impairment

AI Wiesman, J O'Neill, MS Mills, KR Robertson, HS Fox… - Brain, 2018 - academic.oup.com
Combination antiretroviral therapies have revolutionized the treatment of HIV infection, and
many patients now enjoy a lifespan equal to that of the general population. However, HIV …