Age-related changes in GAD levels in the central auditory system of the rat
J Burianova, L Ouda, O Profant, J Syka - Experimental gerontology, 2009 - Elsevier
Changes in the levels of gamma-aminobutyric acid (GABA) are known to occur in different
parts of the brain during aging. In our study we attempted to define the effect that aging has …
parts of the brain during aging. In our study we attempted to define the effect that aging has …
Rhythmic spontaneous activity mediates the age-related decline in somatosensory function
Sensory gating is a neurophysiological process whereby the response to a second stimulus
in a pair of identical stimuli is attenuated, and it is thought to reflect the capacity of the CNS …
in a pair of identical stimuli is attenuated, and it is thought to reflect the capacity of the CNS …
Lifelong plasticity in the rat auditory cortex: basic mechanisms and role of sensory experience
E de Villers-Sidani, MM Merzenich - Progress in brain research, 2011 - Elsevier
The rodent auditory cortex has provided a particularly useful model for studying cortical
plasticity phenomenology and mechanisms, both in infant and in adult animal models. Much …
plasticity phenomenology and mechanisms, both in infant and in adult animal models. Much …
GABA through the ages: regulation of cortical function and plasticity by inhibitory interneurons
K Lehmann, A Steinecke, J Bolz - Neural plasticity, 2012 - Wiley Online Library
Inhibitory interneurons comprise only about 20% of cortical neurons and thus constitute a
clear minority compared to the vast number of excitatory projection neurons. They are …
clear minority compared to the vast number of excitatory projection neurons. They are …
GABA levels and measures of intracortical and interhemispheric excitability in healthy young and older adults: an MRS-TMS study
L Hermans, O Levin, C Maes, P van Ruitenbeek… - Neurobiology of …, 2018 - Elsevier
Edited magnetic resonance spectroscopy (MRS) and transcranial magnetic stimulation
(TMS) have often been used to study the integrity of the GABAergic neurotransmission …
(TMS) have often been used to study the integrity of the GABAergic neurotransmission …
Occipital GABA levels in older adults and their relationship to visual perceptual suppression
Several studies have attributed certain visual perceptual alterations in older adults to a likely
decrease in GABA (Gamma Aminobutyric Acid) concentration in visual cortex, an …
decrease in GABA (Gamma Aminobutyric Acid) concentration in visual cortex, an …
Age-related declines in occipital GABA are associated with reduced fluid processing ability
M Simmonite, J Carp, BR Foerster, L Ossher… - Academic radiology, 2019 - Elsevier
Rationale and Objectives Healthy aging is associated with pervasive declines in cognitive,
motor, and sensory functioning. There are, however, substantial individual differences in …
motor, and sensory functioning. There are, however, substantial individual differences in …
Brain network segregation and glucose energy utilization: relevance for age-related differences in cognitive function
The human brain is organized into segregated networks with strong within-network
connections and relatively weaker between-network connections. This “small-world” …
connections and relatively weaker between-network connections. This “small-world” …
GABA levels in ventral visual cortex decline with age and are associated with neural distinctiveness
Age-related neural dedifferentiation—a decline in the distinctiveness of neural
representations in the aging brain—has been associated with age-related declines in …
representations in the aging brain—has been associated with age-related declines in …
GABA signaling triggered by TMC-1/Tmc delays neuronal aging by inhibiting the PKC pathway in C. elegans
Aging causes functional decline and degeneration of neurons and is a major risk factor of
neurodegenerative diseases. To investigate the molecular mechanisms underlying neuronal …
neurodegenerative diseases. To investigate the molecular mechanisms underlying neuronal …