GABAergic mechanisms have been shown to contribute to cognitive aging in animal models,
but there is currently limited in vivo evidence to support this relationship in humans. It is also …

Unlike age-related brain changes linked to motor activity, neural alterations related to self-
motion perception remain unknown. Using fMRI data, we investigated age-related changes …

Previous studies have shown that older subjects have difficulties discriminating the walking
direction of point-light walkers. In two experiments, we investigated the underlying cause in …

Efficient practice organization maximizes learning outcome. Although randomization of
practice as compared to blocked practice damages training performance, it boosts retention …

Background Alterations in inhibitory processes mediated by gamma-aminobutyric acid type
B (GABA B) receptors may contribute to age-related functional impairments. However …

γ-Aminobutyric acid (GABA) is a potent bioactive amino acid, and several studies have
shown that oral administration of GABA induces relaxation, improves sleep, and reduces …

Purpose: Little is known about neuronal changes during ageing in the visual system of mice
which are increasingly being used as animal models for human visual disorders. Methods …

Abstract Changes in levels of the inhibitory neurotransmitter γ‐aminobutyric acid (GABA)
may underlie aging‐related changes in brain function. GABA and co‐edited …

Cognitive abilities decline with age, but with considerable individual variation. The
neurobiological correlate of this variation is not well described. Functional brain imaging …

Aging is associated with a decline in hormones and an associated decline in GABAergic
function and calcium and ion current dysregulation. Neurosteroid hormones act as direct …