[HTML][HTML] GABA decrease is associated with degraded neural specificity in the visual cortex of glaucoma patients

JW Bang, C Parra, K Yu, G Wollstein… - Communications …, 2023 - nature.com
Glaucoma is an age-related neurodegenerative disease of the visual system, affecting both
the eye and the brain. Yet its underlying metabolic mechanisms and neurobehavioral …

[HTML][HTML] Dietary restriction affects neuronal response property and GABA synthesis in the primary visual cortex

J Yang, Q Wang, F He, Y Ding, Q Sun, T Hua, M Xi - PloS one, 2016 - journals.plos.org
Previous studies have reported inconsistent effects of dietary restriction (DR) on cortical
inhibition. To clarify this issue, we examined the response properties of neurons in the …

Faces emotional expressions: From perceptive to motor areas in aged and young subjects

N Loi, F Ginatempo, A Manca… - Journal of …, 2021 - journals.physiology.org
The role of age in perception and production of facial expressions is still unclear. Therefore,
this work compared, in aged and young subjects, the effects of passive viewing of faces …

Neural correlates of stimulus spatial frequency-dependent contrast detection

J Meng, R Liu, K Wang, T Hua, ZL Lu, M Xi - Experimental Brain Research, 2013 - Springer
Psychophysical studies on human and non-human vertebrate species have shown that
visual contrast sensitivity function (CSF) peaks at a certain stimulus spatial frequency and …

The trajectory of cortical GABA levels across the lifespan: An individual participant data meta-analysis of edited MRS studies

EC Porges, G Jensen, B Foster, RAE Edden, NAJ Puts - bioRxiv, 2020 - biorxiv.org
ABSTRACT GABA is the principal inhibitory neurotransmitter in the human brain and can be
measured with Magnetic Resonance Spectroscopy (MRS). Conflicting accounts report …

Edited magnetic resonance spectroscopy detects an age‐related decline in nonhuman primate brain GABA levels

X He, BB Koo, RJ Killiany - BioMed research international, 2016 - Wiley Online Library
Recent research had shown a correlation between aging and decreasing Gamma‐
aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the brain. However, how …

Functional implications of dynamic DNA methylation for the developing, aging and diseased brain

G Zimmer-Bensch - The DNA, RNA, and Histone Methylomes, 2019 - Springer
Epigenetic mechanisms of gene regulation as the interface between the genome and
environment, control diverse processes in development, aging and disease. As proposed by …

Paired‐Pulse Inhibition in the Auditory Cortex in Parkinson′ s Disease and Its Dependence on Clinical Characteristics of the Patients

E Lukhanina, N Berezetskaya, I Karaban - Parkinson's Disease, 2011 - Wiley Online Library
We aimed to determine the value of the paired‐pulse inhibition (PPI) in the auditory cortex in
patients with Parkinson′ s disease (PD) and analyze its dependence on clinical …

Aging affects fine and coarse coding of orientation information in macaque primary visual cortex

B Zhang, Z Gao, X Wang, Z Yao, G Xu, Z Liang, Y Zhou - Neuroscience, 2020 - Elsevier
Human visual function degrades with age. Previous studies of visual perception have shown
that aged people have worse performance in the coding of orientation information. However …

Effect of physiological aging on binocular vision

FF Yan, H Lv, S Fan, L Chen, Y Wu, CB Huang - PsyCh Journal, 2021 - Wiley Online Library
We see the world with two eyes. Binocular vision provides more ample information through
interocular interaction. Previous studies have shown that aging impairs a variety of visual …