The ever-increasing supply of information combined with the growing knowledge elicitation
capabilities of key emerging technologies presents pharmacovigilance with enormous …

Introduction Pharmacovigilance studies have definitely established that clozapine can cause
myocarditis. Two published reviews suggested that on rare occasions other antipsychotics …

Despite huge technological advances in the capabilities to capture, store, link and analyse
data electronically, there has been some but limited impact on routine pharmacovigilance …

The use of clozapine requires monitoring the absolute neutrophil count because of the risk
of agranulocytosis, but other potentially fatal adverse events associated with clozapine …

Background: The Food and Drug Administration (FDA) in the United States and the
European Medicines Agency (EMA) have recognized social media as a new data source to …

Researchers, regulatory agencies, and the pharmaceutical industry are moving towards
precision pharmacovigilance as a comprehensive framework for drug safety assessment, at …

Introduction: Social media mining could be a possible strategy to retrieve drug safety
information. The mining of social media is a complex process under progressive evolution …

Background: Evidence suggesting adverse drug reactions often emerges unsystematically
and unpredictably in form of anecdotal reports, case series and survey data. Safety trials and …

Drug Safety (DS) is a domain with significant public health and social impact. Knowledge
Engineering (KE) is the Computer Science discipline elaborating on methods and tools for …

Signal detection and management is a key activity in pharmacovigilance (PV). When a new
PV signal is identified, the respective information is publicly communicated in the form of …