Role of Genetics in Diagnosis and Management of Hypertrophic Cardiomyopathy: A Glimpse into the Future

MT Abbas, N Baba Ali, JM Farina, AK Mahmoud… - Biomedicines, 2024 - mdpi.com
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy. It
follows an autosomal dominant inheritance pattern in most cases, with incomplete …

[HTML][HTML] Left Atrial Dysfunction in Apical Hypertrophic Cardiomyopathy: Assessed by Cardiovascular Magnetic Resonance Feature-tracking

Y Yang, M Lu, X Guan, S Zhao… - Journal of Thoracic …, 2024 - journals.lww.com
Purpose: To evaluate the left atrial (LA) function in participants with apical hypertrophic
cardiomyopathy (AHCM) by cardiovascular magnetic resonance feature tracking (CMR-FT) …

Characterization of the circulating transcriptome expression profile and identification of novel miRNA biomarkers in hypertrophic cardiomyopathy

L Guo, Y Cai, B Wang, F Zhang, H Zhao, L Liu… - European Journal of …, 2023 - Springer
Background Hypertrophic cardiomyopathy (HCM), one of the most common genetic
cardiovascular diseases, but cannot be explained by single genetic factors. Circulating …

Left Ventricular Hypertrophy and Hypertrophic Cardiomyopathy in Adult Solid Organ Transplant Recipients

N Reza, A De Feria, T Wang, JL Chowns… - Transplantation …, 2022 - journals.lww.com
Background. Hypertrophic cardiomyopathy (HCM) in pediatric solid organ transplant
recipients has been reported in association with use of calcineurin inhibitors. However, data …

Mitral Valve Prolapse in Obstructive Hypertrophic Cardiomyopathy

C Song, J Cui, X Zheng, J Lu, X Guo, S Wang… - The American Journal of …, 2023 - Elsevier
Obstructive hypertrophic cardiomyopathy (oHCM) and mitral valve (MV) prolapse (MVP) are
the 2 conditions which could cause symptomatic heart failure and sudden cardiac death …

A Novel Truncating Variant in MYBPC3 Causes Hypertrophic Cardiomyopathy

Y Zhang, W Gong, Y Cong, X Zhang, Z Zheng - medRxiv, 2024 - medrxiv.org
Background Familial hypertrophic cardiomyopathy (HCM) is the most common genetic
cardiovascular disease. Related mutations contributing to hypercontractility and poor …

The use of MitraClip for nonobstructive hypertrophic cardiomyopathy with mixed severe mitral valve regurgitation

J Zeng, Q Shu, C Lu, Y Wang - ESC Heart Failure, 2023 - Wiley Online Library
Reports on the treatment of nonobstructive hypertrophic cardiomyopathy (HCM) and severe
mitral valve regurgitation (MR) with transcatheter edge‐to‐edge repair (TEER) are rare …

Deciphering Genotype-Phenotype Associations in Hypertrophic Cardiomyopathy Using Machine Learning

M Glavaški - 2023 - search.proquest.com
Hypertrophic cardiomyopathy (HCM) is the most prevailing heritable cardiomyopathy. HCM
is diagnosed by the existence of left ventricular hypertrophy despite the lack of abnormal …

[HTML][HTML] Establishment of an induced pluripotent stem cell line (ZJULLi004-A) from a hypertrophic cardiomyopathy patient carrying MYBPC3/c. 3764C> A mutation

Y Sun, J Zhou, H Wang, H Wang, X Chen, T Gong… - Stem Cell Research, 2022 - Elsevier
Hypertrophic cardiomyopathy (HCM) is an inherited cardiovascular disease characterized
by left ventricular hypertrophy and a high risk of sudden death. In this study, a skin biopsy …

Gene-Specific Discriminative Echocardiogram Findings in Hypertrophic Cardiomyopathy Determined Using Artificial Intelligence: A Pilot Study

M Glavaški, A Ilić, L Velicki - Cardiogenetics, 2023 - mdpi.com
Hypertrophic cardiomyopathy (HCM) is among the most common forms of cardiomyopathies,
with a prevalence of 1: 200 to 1: 500 people. HCM is caused by variants in genes encoding …